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口服盐酸利多卡因胶浆联合磷酸钠盐在肠镜检查中的效果观察
引用本文:柴先灯,李伦兰,杨桂芳,李杨,孙斌.口服盐酸利多卡因胶浆联合磷酸钠盐在肠镜检查中的效果观察[J].中华全科医学,2021,19(8):1411.
作者姓名:柴先灯  李伦兰  杨桂芳  李杨  孙斌
基金项目:国家自然科学基金项目61976007
摘    要:  目的  探讨口服盐酸利多卡因胶浆联合磷酸钠盐溶液肠道准备方法在普通肠镜检查肠道准备中的应用效果,以提高肠镜检查效率及质量。  方法  选择安徽医科大学第一附属医院2020年4—6月接受普通结肠镜检查的293例患者为研究对象,按随机数字表法随机分为观察组(145例)和对照组(148例)。对照组患者采用传统方法,即分2次服用磷酸钠盐行肠道准备,观察组患者在对照组的基础上于检查前4~6 h加服20 mL盐酸利多卡因胶浆。采用Morisky服药依从性量表、波士顿肠道准备量表、Bubble气泡评分标准、疼痛数字评分法比较2组患者在服药依从性、肠道准备清洁度、肠道气泡评分、检查中患者疼痛程度以及退镜时间、息肉检出率上的差异。  结果  2组患者服药依从性、肠道清洁度、疼痛程度、息肉检出率比较,差异无统计学意义(均P>0.05)。观察组患者肠道气泡评分为(2.57±0.69)分,高于对照组患者(2.24±0.78)分],差异有统计学意义(t=3.833, P<0.001)。观察组患者退镜时间为(6.82±1.23)min,短于对照组患者(7.88±1.77)min],差异有统计学意义(t=5.941, P<0.001)。  结论  口服盐酸利多卡因胶浆联合磷酸钠盐肠道准备方法,能够有效减少肠道内的气泡量,缩短肠镜检查时间,提高肠镜检查效率及质量。 

关 键 词:盐酸利多卡因胶浆    结肠镜    肠道准备    磷酸钠盐    祛泡
收稿时间:2021-02-04

The effect of oral lidocaine hydrochloride mucilage combined with sodium phosphate in colonoscopy
Institution:Gastroenterology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China
Abstract:  Objective  To explore the application effect of oral lidocaine hydrochloride mucilage combined with sodium phosphate solution in bowel preparation in common colonoscopy and to improve the efficiency and quality of colonoscopy.  Methods  Total 293 patients who underwent general colonoscopy in our hospital from April to June 2020 were enrolled and randomly divided into two groups according to the random number table method, including 145 cases in the experimental group and 148 cases in the control group. The patients in the control group used the traditional method of taking sodium phosphate in two doses for bowel preparation. The patients in the experimental group were given 20 mL lidocaine hydrochloride mucilage 4-6 hours before the examination on the basis of the control group. Morisky Medication Compliance Scale, Boston Bowel Intestinal Preparation Scale, Bubble Score, and Pain Numerical Score were used to compare the medication compliance, cleanliness of intestinal preparation, intestinal bubble score, and the degree of pain during the examination between the two groups of patients.  Results  There were no significant difference in medication compliance, intestinal cleanliness, pain degree, and polyp detection rate between the two groups of patients (all P>0.05). The score of the intestinal bubble score of the test group was (2.57±0.69) points, which was higher than the score of the control group (2.24±0.78) points], and the difference was statistically significant (t=3.833, P < 0.001). The time to withdraw the lens in the experimental group was (6.82±1.23) minutes, which was less than (7.88±1.77) minutes in the control group, and the difference was statistically significant (t=5.941, P < 0.001).  Conclusion  The intestinal preparation method of oral lidocaine hydrochloride mucilage combined with sodium phosphate can effectively reduce the amount of bubbles in the intestine, shorten the time of colonoscopy, and improve the efficiency and quality of colonoscopy. 
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