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乳腺癌靶向治疗相关心血管毒性的研究进展
引用本文:王岩,孟文静,佟仲生. 乳腺癌靶向治疗相关心血管毒性的研究进展[J]. 肿瘤防治研究, 2021, 48(5): 524-529. DOI: 10.3971/j.issn.1000-8578.2021.20.1232
作者姓名:王岩  孟文静  佟仲生
作者单位:300060 天津,天津医科大学肿瘤医院乳腺肿瘤内科,国家肿瘤临床医学研究中心,乳腺癌防治教育部重点实验室,天津市恶性肿瘤临床医学研究中心,天津市“肿瘤防治”重点实验室
基金项目:天津市卫生行业重点攻关项目(16KG128);天津市自然科学基金(18JCYBJC91600)
摘    要:乳腺癌是女性常见的恶性肿瘤之一。由于近年来乳腺癌诊疗手段的丰富和靶向治疗药物的广泛应用,乳腺癌患者的生存期较前有所延长,死亡率呈现下降的趋势。然而,与靶向药物治疗相关的心血管毒性在乳腺癌患者治疗过程中的发生率也随之升高,本文就乳腺癌靶向药物治疗相关心血管毒性的研究进展作一综述。

关 键 词:乳腺癌  靶向治疗  心血管毒性  
收稿时间:2020-10-23

Advances in Cardiovascular Toxicity Associated with Targeted Therapy for Breast Cancer
WANG Yan,MENG Wenjing,TONG Zhongsheng. Advances in Cardiovascular Toxicity Associated with Targeted Therapy for Breast Cancer[J]. Cancer Research on Prevention and Treatment, 2021, 48(5): 524-529. DOI: 10.3971/j.issn.1000-8578.2021.20.1232
Authors:WANG Yan  MENG Wenjing  TONG Zhongsheng
Affiliation:Department of Breast Medical Oncology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education; Tianjin’s Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
Abstract:Breast cancer is one of the most common malignant tumors in women. Because of the abundance of diagnosis and treatment methods and the wide application of targeted therapy drugs in recent years, the survival time of breast cancer patients is longer than before and the mortality rate shows a downward trend. However, the incidence of cardiovascular toxicity associated with targeted drug therapy in breast cancer patients is also increasing. This article reviews the research progress of cardiovascular toxicity associated with targeted drug therapy in breast cancer.
Keywords:Breast cancer   Targeted therapy   Cardiovascular toxicity  
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