地塞米松辅助治疗细菌性脑膜炎的研究

目的：探讨细菌性脑膜炎早期辅用地塞米松的临床效果。方法：59例急性细菌性脑膜炎病人分为两组，在接受敏感抗生素治疗同时，一组加用地塞米松10－20mg/d,7天。结果：用与不用地塞米松组痊愈率无差异，但退热时间，意识障碍恢复时间及颈强直消失时间地塞米松组明显优于对照组。结论：严重的细菌性脑膜炎病人辅以地塞米松治疗是有益的。

Study on dexamethasone adjunctive treatment of bacterial meningit is in adults

ve To study the clinical benefit of adjunctive dexamethasone therapy for bacterial meningitis in adults. Methods Fivety nine patients of acute bacterial meningitis were randomized to two treatment groups. In addition to standard antibiotic therapy, one group received dexamethasone 10 - 20mg/d for 7 day. Result The difference of rate of cured patients between the dexamethasone group and aother group was not significant But time to defevesence, return of consciousness and disappearance of neck rigidity was shorter the dexamethasone group than other group. Conclusion In adults, with bacterial meningitis, especially in severe cases, the adjunctive use of dexamethasone may be beneficial.