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Cancer immunotherapy: A paradigm shift in the treatment of advanced urologic cancers
Authors:David M. Gill  Neeraj Agarwal
Affiliation:Department of Medicine, Huntsman Cancer Institute, Salt Lake City, UT
Abstract:The recent resurgence of immunotherapy has transformed the therapeutic field of advanced urologic cancers. In this seminars issue, we evaluate the role of emerging and recently approved immunotherapeutic agents in advanced prostate, urothelial, and renal cell carcinoma. In each of these fields, we discuss recent regulatory approvals as well as promising ongoing clinical trials. Finally, we discuss incidence and management of immune related adverse events specifically associated with PD-1/PD-L1 inhibitors.
Keywords:Systemic immunotherapy  Urologic oncology  Checkpoint inhibitors  Cancer vaccines
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