中西医结合治疗慢性萎缩性胃炎临床观察

目的：观察中西医结合治疗慢性萎缩性胃炎临床疗效。方法：选该病患者69例,随机分为两组。对照组33例用胶体果胶铋、黄连素片、维酶素片治疗;治疗组36例在对照组用药的基础上加用中药治疗,疗程2月。结果：治疗组痊愈4例,显效23例,有效5例,无效4例,总有效率为88.89%（95%CI=78.62%~99.16%）;对照组痊愈2例,显效12例,有效9例,无效10例,总有效率为69.70%（95%CI=54.02%~85.38%）;两组综合疗效比较（u=2.437 8,P=0.015 5）,有显著性差异;治疗组治疗后组间症状积分显著优于对照组（t=-5.596 5,P〈0.01）。结论：中西医结合治疗慢性萎缩性胃炎较单纯西医治疗为优,其收益为OR=0.29（但95%CI跨过1）,NNT=5（95%CI=2.6~5 000.0）。

Clinical Observation of Therapy of Integrated Chinese and Western Medicine on Chronic Atrophic Gastritis

Objective： To observe the clinical curative effect of therapy of integrated Chinese and western medicine on chronic atrophic gastritis.Method： 69 cases with chronic atrophic gastritis were divided into two groups randomly.33 cases in control group were treated with Colloidal bismmth pectin,tablet berberine and tablet Wei-mei-su.36 cases in treatment group were treated with Chinese medicine on the ground of above treatment.The course of treatment included 2 months.Result： In treatment group 4 cases were recovered,23 ones excellent,5 ones effective and 4 ones ineffective.The total effective rate was 88.89%（95%CI=78.62%-99.16%）.In control group 2 cases were recovered,12 ones excellent,9 ones effective and 10 ones ineffective.The total effective rate was 69.70%（95%CI=54.02%-85.38%）.There was significant difference between the two groups on the effective rate（u=2.437 8,P=0.015 5）.And after treatment symptom score in treatment group was better than that in control group（t=-5.596 5,P0.01）.Conclusion： The curative effect of therapy of integrated Chinese and western medicine is better than that of western medicine on chronic atrophic gastritis,OR=0.29（but 95%CI1）,NNT=5（95%CI=2.6-5000.0）.