| 胎肝细胞质液对小鼠IL－2系统的影响 |
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| 引用本文： | 戴盛明,肖桂元,周少雄. 胎肝细胞质液对小鼠IL－2系统的影响[J]. 右江民族医学院学报, 1996, 0(2) |
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| 作者姓名： | 戴盛明 肖桂元 周少雄 |
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| 作者单位： | 广东省湛江市中心人民医院 |
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| 摘 要： | 用自制胎肝细胞质液（ＦＬＣ）对小鼠ＩＬ２系统的影响进行研究，结果表明ＦＬＣ对正常小鼠体内Ｔ淋巴细胞有诱生ＩＬ２的作用（Ｐ＜００５），可明显促进淋巴细胞ｍＩＬ２Ｒ的表达（Ｐ＜００１）和血清ｓＩＬ２Ｒ水平的降低（Ｐ＜００５）；对环磷酰胺免疫抑制后小鼠的ＩＬ２诱生、ｍＩＬ２Ｒ表达均有所改善（分别为Ｐ＜００５，Ｐ＜００１），提示ＦＬＣ对小鼠Ｔ淋巴细胞有一定程度活化和诱导ＩＬ２产生的作用，可降低小鼠血清ｓＩＬ２Ｒ水平。
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| 关 键 词： | 胎肝细胞质液；IL－2；mIL－2R；sIL－2R |
Effect of Fetal Liver Cytosol on IL 2 System in Mice |
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| Dai Shengming,Xiao Guiyuan,Zhou Shaoxiong Instiute of Clinical Medicine,Zhanjiang,Guangdong. Effect of Fetal Liver Cytosol on IL 2 System in Mice[J]. Journal of Youjiang Medical College For Nationalities, 1996, 0(2) |
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| Authors: | Dai Shengming Xiao Guiyuan Zhou Shaoxiong Instiute of Clinical Medicine Zhanjiang Guangdong |
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| Affiliation: | Dai Shengming,Xiao Guiyuan,Zhou Shaoxiong Instiute of Clinical Medicine,Zhanjiang,Guangdong 524037 |
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| Abstract: | The effect of Fetal Liver Cytosol (FLC) on IL 2 system in mice was studied . Results indicated that FLC could induce IL 2 production of T lymphocytes, (P<0 05) and Obviously promote the expression of mIL 2R and decreaes the level of serum sIL 2R FLC could ameliorate resistance to the immumosuppressive effect caused by cyclophosphamide to IL 2 induction and mIL 2R expression, It suggested that FLC could activate T lymphocytes in certain degree, induce IL 2 production and reduce the level of sIL 2R in mice. |
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| Keywords: | fetal liver cytosol II 2 mIL 2R sIL 2R |
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