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Stability of enalapril repackaged into monitored dosage system
Authors:Héctor R. Loscertales  Pilar Modamio  Cecilia F. Lastra  Antonio J. Braza  Gonzalo Tobaruela
Affiliation:Clinical Pharmacy and Pharmacotherapy Unit, Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
Abstract:A monitored dosage system (MDS) is a professionally prepared blister-type repackaging system used to improve medication adherence. The objective of this study was to determine the stability of enalapril tablets, a widely prescribed drug, commonly used by the elderly but potentially unstable in MDSs. No degradation of enalapril tablets repackaged into MDSs was observed during the 60 day study period.
Keywords:Drug stability  Enalapril  Monitored dosage system  Patient safety
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