| 板蓝根多糖对猪繁殖与呼吸综合征疫苗免疫猪T细胞亚群的影响 |
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| 引用本文： | 张红英,赵现敏,崔保安,夏平安,邱妍,胡梅,王远阁. 板蓝根多糖对猪繁殖与呼吸综合征疫苗免疫猪T细胞亚群的影响[J]. 中国免疫学杂志, 2007, 23(2): 134-137 |
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| 作者姓名： | 张红英 赵现敏 崔保安 夏平安 邱妍 胡梅 王远阁 |
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| 作者单位： | 1. 河南农业大学牧医工程学院,河南省动物性食品安全重点实验室,郑州,450002
2. 南京农业大学动物医学院,南京,210095 |
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| 基金项目： | 国家食品安全重大攻关专项项目;河南省高校杰出科研创新人才工程项目 |
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| 摘 要： | 目的：研究板蓝根多糖对猪繁殖与呼吸综合征灭活疫苗免疫猪T细胞亚群及抗体的影响.方法：以板蓝根多糖作为免疫增强剂联合猪繁殖与呼吸综合征灭活疫苗免疫仔猪,通过流式细胞仪检测猪外周血CD3^＋、CD4^＋、CD8^＋细胞百分数,并用ELISA法检测猪血清中抗猪繁殖障碍与呼吸道综合征病毒抗体水平.结果：板蓝根多糖能显著提高仔猪的CD3^＋、CD8^＋淋巴细胞的百分数和特异性抗体滴度.结论：板蓝根多糖能显著增强猪对常规灭活病毒疫苗的免疫应答能力.
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| 关 键 词： | 板蓝根多糖 免疫增强剂 仔猪 猪繁殖与呼吸综合征灭活疫苗 T细胞亚群 |
| 文章编号： | 1000-484X（2007）02-0134-04 |
| 修稿时间： | 2006-06-202006-08-07 |
Effects of IRPS on T subpopulations in the immune response to porcine reproductive and respiratory syndrome attenuated virus vaccine |
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| ZHANG Hong-Ying,ZHAO Xian-Min,CUI Bao-An,XIA Ping-An,QIU Yan,HU Mei,WANG Yuan-Ge. Effects of IRPS on T subpopulations in the immune response to porcine reproductive and respiratory syndrome attenuated virus vaccine[J]. Chinese Journal of Immunology, 2007, 23(2): 134-137 |
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| Authors: | ZHANG Hong-Ying ZHAO Xian-Min CUI Bao-An XIA Ping-An QIU Yan HU Mei WANG Yuan-Ge |
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| Affiliation: | College of Animal Husbandry and Veterinary Medicine, Henan Agricultural University; Key Laboratory of Animal-derived Food Safety, Henan Province, Zhengzhou 450002, China |
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| Abstract: | Objective:To research the effects of Isatis root polysaccharide(IRPS)on T subpopulations of piglets in the immune response to porcine reproductive and respiratory syndrome attenuated virus vaccine.Methods:T lymphocytes subpopulations in the piglets pheripheral blood were tested at different time with porcine reproductive and respiratory syndrome attenuated virus vaccine(PRRS vaccine)with or without IRPS by cytofluorometry.The serum titer of special antibody were tested by PRRS antibody test kit.Results:IPRS could improve the proportion of CD3 and CD8 in the piglets pheripheral blood and boost the production of special antibody.Conclusion:The results suggested that IRPS co-inoculated with PRRS vaccine could enhance immune response of pigs.It is a potential immunostimulatory for pigs. |
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| Keywords: | IRPS Immunologic adjuvant Piglets Porcine reproductive and respiratory syndrome attenuated virus vaccine T lymphocyte subpopulations |
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