肾结石合并肾盂鳞状细胞癌的早期诊断与治疗(附2例报告)

本研究报告肾结石合并肾盂鳞状细胞癌2例,结合相关文献探讨其早期诊断及治疗方法.该2例均有典型肾绞痛病史及合并血尿和脓肿,CT检查提示肾盂癌1例.其中1例术中经冰冻病理确诊后,行根治性患肾切除术,术后随访18个月无复发;另1例术后行全身化疗,4个月后死于全身衰竭.2例病理诊断均为鳞状细胞癌.分析认为,肾结石合并肾盂鳞状细胞癌恶性程度高、预后差,早期诊断较为困难,排泄性尿路造影及CT等检查有助于明确诊断,治疗以根治性患肾切除为主.

Early diagnosis and treatment of renal calculi complicated with renal squamous carcinoma:A report of 2 cases

From 1983 to 2000, 2 patients with squamous cell carcinoma of the renal pelvis associated with renal calculi were treated in our department. The literature was reviewed to discuss the diagnosis and the treatment. Both of the 2 patients presented with typical renal colic, gross hematuria and renal abscess. In one patient, renal pelvic tumor was diagnosed by CT before operation and radical nephrectomy was carried out after squamous cell carcinoma was detected with frozen section during operation. No recurrence was developed during a follow-up of 18 months. Another patient received systemic chemotherapy and died from cancer collapse after 4 months. Squamous cell carcinoma of the renal pelvis is uncommon and associated with renal calculi. Typically, these are poorly differentiated tumors with poor prognosis. Early diagnosis is difficult and radical nephrectomy is the first-choice treatment.