A study of HLA antigen association in localized and generalized granuloma annulare |
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| Authors: | R FRIEDMAN-BIRNBAUM O GIDEONI R BERGMAN S POLLACK |
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| Institution: | Department of Dermatology, Tissue Typing Laboratory, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;Division of Clinical Immunology, Tissue Typing Laboratory, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel |
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| Abstract: | HLA-A and -B antigen frequencies were studied in 78 patients, 35 with localized granuloma annulare and 43 with generalized granuloma annulare (GA). Twenty-eight patients in each group were also typed for HLA-DR antigens. A group of 200 healthy age-matched subjects served as controls. HLA-A31 and B35 were increased significantly in patients with generalized GA, but not in the localized form. HLA-DR antigen distribution showed no significant variation. |
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