C型臂引导下经支气管镜介入治疗空洞型肺结核30例疗效观察

目的:探讨C型臂引导下经支气管镜介入治疗空洞型肺结核的临床疗效及应用价值。方法:将60例空洞型肺结核住院患者随机分为常规治疗组(对照组)和介入治疗组(观察组)。对照组采用3HRA(E)ZV/6HR化疗方案治疗,观察组在此基础上加用C型臂引导下气管镜介入治疗。结果:疗程结束后,观察组痰菌阴转率为70.0%(21/30),病灶显著吸收率为63.3%(19/30),明显高于对照组[36.7%(11/30),33.3%(10/30),P<0.05]。观察组空洞闭合率为36.7%,明显高于对照组[13.3%,P<0.05]。两组均未发生明显不良反应。结论:C型臂引导下经支气管镜介入给药是治疗空洞型肺结核较为有效和安全的治疗方法。

Study on efficacy of interventional treatment by bronchofiberscope under C-arm X-ray machine-guided for cavitary pulmonary tuberculosis

Objective: To evaluate the feasibility,clinical efficacy and treatment value of interventional treatment by bronchofiberscope under C-arm X-ray machine-guided for cavitary pulmonary tuberculosis.Methods: Sixty patients with cavitary pulmonary tuberculosis were randomly as signed to a treatment group and a control group.All patients received chemotherapy with 3HRA(E)ZV/6HR.Meanwhile,patients in the treatment group were given interventional treatment by bronchofiberscope under C-arm X-ray Machine-guided.Results: At the end of the course,the rate of sputum negative and foci absorption were 70.0%(21/30) and 63.3%(19/30)in the treatment group,respectively,which were higher than those of the control with statistical significance(P<0.05).the rate of cavity closure was 36.7% that higher than those of the control with statistical significance(P<0.05).No obvious severe adverse effects were found with in the treatment group.Conclusion: the interventional treatment by bronchofiberscope under C-arm X-ray machine-guided is an effective and safe treatment approach for patients with cavitary pulmonary tuberculosis,therefore,it is worth to be applied clinically.