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血必净对急性重度有机磷中毒患者血浆白细胞介素18的影响
引用本文:郭景瑞,米慧,张欣华.血必净对急性重度有机磷中毒患者血浆白细胞介素18的影响[J].医学综述,2010,16(24).
作者姓名:郭景瑞  米慧  张欣华
摘    要:目的探讨血必净对急性重度有机磷中毒(ASOP)患者血浆白细胞介素18(IL-18)的影响。方法急性重度有机磷中毒患者108例,随机单盲分为血必净组55例,常规治疗组53例,采用酶联免疫吸附法测定血浆IL-18水平。结果血必净组和常规治疗组治疗后IL-18水平均有明显降低,而血必净组的疗效比常规治疗组更显著(P<0.05)。结论血必净可通过降低IL-18水平减少并发症的发生,提高治愈率、降低病死率。

关 键 词:血必净  有机磷中毒  白细胞介素18  中间综合征

Effect of Xuebijing on Interleukin 18 in Patients with Acut Severe Organophosphate Poisoning
GUO Jing-rui,MI Hui,ZHANG Xin-hua.Effect of Xuebijing on Interleukin 18 in Patients with Acut Severe Organophosphate Poisoning[J].Medical Recapitulate,2010,16(24).
Authors:GUO Jing-rui  MI Hui  ZHANG Xin-hua
Abstract:Objective To assess the effects of Xuebijing on plasma interleukin(IL)-18 levels in patients with acute severe organophosphate poisoning(ASOP).Methods 108 patients with ASOP were randomly divided into receive Xuebijing plus conventional treatment group(n=55)and conventional treatment alone(n=53).To detect the plasma IL-18 levels of the patients with ASOP by an enzyme linked immunosorbent assay method.Results IL-18 of post-treatment decreased obviously,and the effects of Xuebijing group was better than conventional treatment group(P<0.05).Conclusion Through decreasing level of IL-18 in blood plasm,xuebijing could reduce complications,rasie cure rate and lower case-fatality rate.
Keywords:Xuebijing  Organophosphate poisoning  IL-18  Intermediate syndrome
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