Intrauterine insemination: evaluation of the results according to the woman's age, sperm quality, total sperm count per insemination and life table analysis

We report on 332 infertile couples who underwent 1115 cyclesof intrauterine insemination (IUI) with washed husband's semen.The indication for IUI was an abnormal post-coital test dueto either a male or cervical infertility factor. The mean numberof IUI cycles per patient was 3.4, the overall pregnancy rate18, 7%, and the pregnancy rate per cycle 5.6%. The cumulativepregnancy rate calculated by life table analysis showed that16.0% of pregnancies occurred in the first three treatment cycles,while the cumulative pregnancy rate was 26.9% by the sixth cycle.The outcome of the therapy was adversely affected if the woman'sage was >39 years and/or total motile sperm count per inseminationwas <1X106. No pregnancy occurred in women older than 44years or in cases with a total motile sperm count before semenpreparation of <1X106.