Effects of whey protein supplementation on adiposity,body weight,and glycemic parameters: A synthesis of evidence |
| |
| Affiliation: | 1. Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada;2. St. John''s Medical College, Bangalore, India;3. Masira Research Institute Medical School, Universidad de Santander, Bucaramanga, Colombia;4. UiTM Selayang, Selangor and UCSI University, Cheras, Kuala Lumpur, Malaysia;5. Universitas Indonesia, National Cardiovascular Centre, Jakarta, Indonesia;6. Fattouma Bourguiba University Hospital and University of Monastir, Tunisia;7. Eminence, Dhaka, Bangladesh;8. Université Laval Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec City, Canada;9. University of the Philippines, Manila, Philippines;1. Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, People''s Republic of China;2. Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen University Health Science Center, Shenzhen, Guangdong, People''s Republic of China;3. Department of Social Medicine and Health Service Management, College of Public Health, Zhengzhou University, Zhengzhou, Henan, People''s Republic of China;1. Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China;2. Department of Cardiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, 215000, China;3. Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, Jiangsu, 210029, China;1. Medicina 7.2, Hospital Curry Cabral, Centro Hospitalar Universitário Lisboa Central (CHULC), Portugal;2. Endocrinologia, Hospital Curry Cabral, Centro Hospitalar Universitário Lisboa Central (CHULC), Portugal;1. Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran;2. Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran;3. School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran;4. Science and Engineering of Food Industry, Islamic Azad University of Qazvin, Qazvin, Iran;5. Department of Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran;6. School of Pharmacy and Bio Engineering, Keele University, Staffordshire, UK;7. Keele University School of Medicine, Keele University, Staffordshire, UK;8. School of Pharmacy, MCPHS University, Boston, MA, 02115, USA;1. Department of Medicine, Studium Patavinum, University of Padova, Padua, Italy;2. S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy;3. Department of Clinical and Experimental Medicine, University of Pisa, Italy;4. Department of Medical and Surgical Science, University of Perugia, Perugia, Italy;5. Alma Mater Studiorum University of Bologna, Bologna, Italy;6. Department of Clinical and Experimental Sciences, University of Brescia, Italy;7. Department of Geriatric and Intensive Care Medicine, Careggi Hospital and University of Florence, Italy;8. Department of Internal Medicine, University of Genoa and Policlinico San Martino, Genova, Italy;9. Department of Life, Health and Environmental Sciences, University of L''Aquila, L''Aquila, Italy;10. Italian Society of General Medicine (SIMG), Avezzano, L''Aquila, Italy;11. Department of Cardiovascular, Neural and Metabolic Sciences, Clinica Medica, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy;12. Department of Clinical Medicine and Surgery, “Federico II” University of Naples Medical School, Naples, Italy;13. Department of Medicine, University of Padua, Padua, Italy;14. Biomedical Department of Internal Medicine and Specialistics, University of Palermo, Palermo, Italy;15. Hospital S. Maria della Misericordia, Perugia, Italy;p. Department of Medicine and Surgery, University of Insubria, Varese, Italy;q. CNR-IFC, Clinical Epidemiology of Renal Diseases and Hypertension, Reggio Cal Unit, Reggio Calabria, Italy;r. Department of Public Health, “Federico II” University of Naples, Napoli, Italy;s. Department of Medicine - DIMED, University of Padova, Medicina Interna 1, Ca’ Foncello University Hospital, Treviso, Italy;t. Department of Emergency and Organ Transplantation - Nephrology, Dialysis and Transplantation Unit, Aldo Moro University of Bari, Bari, Italy;u. Department of Internal Medicine, Hypertension Unit, General Hospital, Rovigo, Italy;v. Cardiology IV, ‘A. De Gasperis’ Department, Niguarda Ca’ Granda Hospital, Health Science Department, Milano-Bicocca University, Milano, Italy;w. Hypertension Unit, Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University of Rome Sapienza, Sant’Andrea Hospital, Rome, Italy;x. Department of Advanced Biomedical Sciences, “Federico II” University of Naples, Napoli, Italy;y. Department of Medical Basic Sciences, Neurosciences and Sense Organs, University of Bari Medical School, Bari, Italy;z. Department of Medicine and Cardiopulmonary Rehabilitation. Maugeri Care and Research Institutes, IRCCS Tradate, Varese, Italy;11. IRCCS Neuromed, Pozzilli (IS), Italy |
| |
| Abstract: | AimsThe aim of this review was to analyze the evidence of whey protein supplementation on body weight, fat mass, lean mass and glycemic parameters in subjects with overweight or type 2 diabetes mellitus (T2DM) undergoing calorie restriction or with ad libitum intake.Data synthesisOverweight and obesity are considered risk factors for the development of chronic noncommunicable diseases such as T2DM. Calorie restriction is a dietary therapy that reduces weight and fat mass, promotes the improvement of glycemic parameters, and decreases muscle mass. The maintenance of muscle mass during weight loss is necessary in view of its implication in preventing chronic diseases and improving functional capacity and quality of life. The effects of increased protein consumption on attenuating muscle loss and reducing body fat during calorie restriction or ad libitum intake in overweight individuals are discussed. Some studies have demonstrated the positive effects of whey protein supplementation on improving satiety and postprandial glycemic control in short term; however, it remains unclear whether long-term whey protein supplementation can positively affect glycemic parameters.ConclusionsAlthough whey protein is considered to have a high nutritional quality, its effects in the treatment of overweight, obese individuals and those with T2DM undergoing calorie restriction or ad libitum intake are still inconclusive. |
| |
| Keywords: | Whey protein Body weight maintenance Calorie restriction Obesity |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
