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| 血清内脂素在2型糖尿病合并冠心病中的临床意义 | |
| 引用本文： | 柴若楠,吕肖峰,张绍维,阎鸿,李鹏飞,刘静,王巍,罗晶,徐涤非,高伟.血清内脂素在2型糖尿病合并冠心病中的临床意义[J].第三军医大学学报,2009,31(5). |
| 作者姓名： | 柴若楠 吕肖峰 张绍维 阎鸿 李鹏飞 刘静 王巍 罗晶 徐涤非 高伟 |
| 作者单位： | 1. 北京军区总医院内分泌科,北京,100000 2. 解放军202医院内分泌科,沈阳,110005 3. 解放军202医院急诊科,沈阳,110005 4. 沈阳医学院环境教研室,沈阳,110031 5. 第三军医大学新桥医院检验科,重庆,400038 |
| 摘 要： | 目的 分析血清内脂索在2型糖尿病及其合并冠心病中的变化,并探讨内脂素与糖尿病或/和冠心病的相关关系.方法 依据WHO的糖尿病诊断标准随机选择2型糖尿病(T2DM)患者61例,经心电图及冠脉造影检查分为:单纯T2DM组(DM)18例、T2DM合并冠心病(CHD)组(DC)43例以及正常对照组(NC)29例,其中DM组均为新诊断患者.经统计学分析3组间一般资料具有可比性.结果 DM组及DC组血清内脂素浓度水平显著高于健康人对照组(t=4.992 1,P<0.05;t=4.722,P<0.05).DC组患者血清内脂素水平与DM组对照组有显著下降(t=4.236,P<0.05).结论 2型糖尿病患者内脂素水平下降可能提示冠心病的发生或加重,在2型糖尿病合并冠心病诊断和治疗中可能具有一定的意义. |
| 关 键 词： | 糖尿病 内脂素 2型糖尿病合并冠心病 降糖作用 |
Correlation of blood serum visfatin with type 2 diabetes mellitus complicated with coronary artery disease |
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| CHAI Ruo-nan,LU Xiao-feng,ZHANG Shao-wei,YAN Hong,LI Peng-fei,LIU Jing,WANG Wei,LUO Jing,XU Di-fei,GAO Wei.Correlation of blood serum visfatin with type 2 diabetes mellitus complicated with coronary artery disease[J].Acta Academiae Medicinae Militaris Tertiae,2009,31(5). | |
| Authors: | CHAI Ruo-nan LU Xiao-feng ZHANG Shao-wei YAN Hong LI Peng-fei LIU Jing WANG Wei LUO Jing XU Di-fei GAO Wei |
| Institution: | CHAI Ruo-nan1,LU Xiao-feng1,ZHANG Shao-wei2,YAN Hong3,LI Peng-fei4,LIU Jing5,WANG Wei2,LUO Jing2,XU Di-fei2,GAO Wei2(1Department of Endocrinology,General Hospital of Beijing Military Command,Beijing 100000,2Department of Endocrinology,3Emergency Department,No.202 Hospital of PLA,Shenyang 110005,4Department of Environementology,Shenyang Medical College,Shenyang 110031,5Department of Laboratory Medicine,Xinqiao Hospital,Third Military Medical University,Chongqing 400037,China) |
| Abstract: | Objective To study the level changes of blood serum visfatin during the development of coronary artery disease(CAD) in type 2 diabetes mellitus patients,and to find out the relationship of visfatin with type 2 diabetes mellitus(T2DM) caused CAD.MethodsAccording to WHO Diabetes Mellitus diagnosis standard,61 T2DM patients were selected randomly.By electrocardiogram and angiography,the patients were divided into 2 groups: T2DM(n=18) and T2DM complicated with CAD(DC,n=43).Another 29 healthy subjects were inclu... |
| Keywords: | diabetes mellitus visfatin type 2 diabetes mellitus related coronary artery disease hypoglycemic effect |
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