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Edinger-Westphal nucleus: cholecystokinin immunocytochemistry and projections to spinal cord and trigeminal nucleus in the cat |
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| Authors: | R. Maciewicz B.S. Phipps J. Grenier C.E. Poletti |
| Affiliation: | 1. The Stanley Cobb Laboratory for Psychiatric Research and the Department of Neurology, The Massachussetts General Hospital and Harvard Medical School, Boston, MA 02114, U.S.A.;2. The Stanley Cobb Laboratory for Psychiatric Research and the Department of Psychiatry, The Massachusetts General Hospital and Harvard medical School, Boston, MA 02114, U.S.A.;3. The Stanley Cobb Laboratory for Psychiatric Research and the Department of Neurosurgery, The Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, U.S.A. |
| Abstract: | Immunocytochemical methods were used to determine the distribution of cells with cholecystokinin-like immunoreactivity (CCK-LI) in the cat Edinger-Westphal complex (EW). Numerous cells with CCK-LI are found throughout the length of EW. The distribution and frequency of such cells are similar to the pattern of EW neurons that show substance P-like immunoreactivity (SP-LI). Companion retrograde transport experiments reveal that EW neurons which project to spinal cord or the region of the caudal trigeminal nucleus are found throughout the length of EW, and that some EW neurons which project to spinal cord also show CCK-LI. |
| Keywords: | Edinger-Westphal nucleus cholecystokinin spinal cord trigeminal nucleus |
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