| 胃癌中生长抑素表达的临床病理意义及DNA含量分析 |
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| 引用本文： | 王鲁平,虞积耀,丁华野.胃癌中生长抑素表达的临床病理意义及DNA含量分析[J].解放军医学杂志,1998,23(3):175-177. |
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| 作者姓名： | 王鲁平 虞积耀 丁华野 |
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| 作者单位： | 北京军区总医院 |
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| 摘 要： | 应用免疫组化及图像分析技术观察１４０例组织学类型胃癌中生长抑素的表达，并随其中１２７例。
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| 关 键 词： | 胃肿瘤 生长抑素 基因表达 临床病理 DNA |
CLINICOPATHOLOGIC SIGNIFICANCE OF GENE EXPRESSION AND DNA CONTENT ANALYSIS OF SOMATOSTATIN IN GASTRIC CARCINOMA |
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| Wang Luping,Yu Jiyao,Ding Huaye et al.CLINICOPATHOLOGIC SIGNIFICANCE OF GENE EXPRESSION AND DNA CONTENT ANALYSIS OF SOMATOSTATIN IN GASTRIC CARCINOMA[J].Medical Journal of Chinese People's Liberation Army,1998,23(3):175-177. |
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| Authors: | Wang Luping Yu Jiyao Ding Huaye |
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| Institution: | Wang Luping,Yu Jiyao,Ding Huaye et al. General Hospital of Beijing Command,Beijing 100700 |
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| Abstract: | Expressions of somatostatin(SS) in 140 cases of gastric carcinoma(GC) were observed by immunohistochemistry and DNA analysis. Of them, 127 cases were followed up. SS positive gastric carcinoma was demonstrated in 36 cases (25 7%). Expression of SS in GC was not related to histological types, differentiation and metastasis of lymphnodes, and was related to prognosis. The patients of SS postive GC survived longer than SS negative GC( P <0 01). DNA analysis showed that there were more 3 4C,5C cells and less>5C cells in SS positive GC group than in SS negative GC group. The results suggested that SS not only could inhibit growth of GC cells, but had better prognosis in patients with SS positive GC cells. |
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| Keywords: | stomach neoplasms somatostatin gene expression |
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