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Ghrelin与动脉粥样硬化
引用本文:王丽.Ghrelin与动脉粥样硬化[J].心血管病学进展,2010,31(3):476-478.
作者姓名:王丽
作者单位:重庆医科大学第二临床学院老年病科,重庆,400010
摘    要:Ghrelin是近年来发现的一种促进生长激素分泌的多肽,是生长激素促分泌物受体的内源性配体。研究发现,ghrelin除了具有增加摄食及调节能量代谢的作用外,还具有降低血压、对抗炎症反应、保护血管内皮细胞等多种生物学效应,提示其在心血管疾病尤其是在动脉粥样硬化方面具有潜在的治疗效应。

关 键 词:ghrelin  动脉粥样硬化  内皮细胞

Ghrelin and Atherosclerosis
WANG Li.Ghrelin and Atherosclerosis[J].Advances in Cardiovascular Diseases,2010,31(3):476-478.
Authors:WANG Li
Institution:WANG Li,CHEN Qing-wei(Department of Geriatrics,The Second Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400010,China)
Abstract:Ghrelin,a recently discovered peptide hormone with strong growth hormone releasing activity,is an endogenous ligand of the growth hormone secretagogue receptor.At present,researchers have found that ghrelin is able to increase food intake and regulate energy metabolism.In addition,ghrelin is thought to lower blood pressure,fight inflammation,and protect vascular endothelial cells.This suggests that ghrelin has a potential therapeutic effect against atherosclerosis.
Keywords:ghrelin
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