泌尿道医院感染病原菌耐药性及临床的用药分析

目的:为临床合理使用抗菌药物提供参考.方法: 采用前瞻性调查的方法进行留置导尿管所致泌尿道医院感染病例监测.结果:361例送检尿标本培养分离病原菌372株,其中革兰阳性球菌占34.9%,革兰阴性杆菌占31.2%,真菌占33.9%,不论是革兰阳性球菌还是革兰阴性杆菌都表现出极高的多重耐药性.临床药师监测干预病例205例,根据我院病原菌耐药谱及药敏结果,用药的泌尿道感染治疗有效率为98.3%;经验用药的治疗有效率为84.1%.结论:临床药师根据病原菌耐药谱及药敏结果,督促医生合理选用抗菌药物,提高了泌尿道感染的治疗有效率.

Analysis of pathogenic bacterial drug resistance and drug treatment of urinary tract nosocomial infection

Objective: To provide scientific basis for clinical rational use of antibiotics. Methods: Patients with urinary tract infections in our hospital led by indwelling catheter were reviewed prospectively. Results: A total of 372 strains were detected from the urine culture of 361 patients, of which, 34.9% were Gram-positive bacteria, 31.2% were Gram-negative bacteria, and 33.9% were fungi. Both Gram-positive and Gram-negative showed multi-drug resistance. At the same time, clinical pharmacists interfered in drug treatment of 205 patients. Medication efficiency in urinary tract infection were 98.3% according to the data of the bacteria pathology and antibiotic susceptivity and 84.1% according to experience. Conclusions: Clinical pharmacists supervised clinicians to adjust the use of antibiotics rationally, which raised medication efficiency in urinary tract infection.