| 乳癌组织p73基因的分析 |
| |
| 引用本文： | 杨开颜.乳癌组织p73基因的分析[J].温州医学院学报,2003,33(6):369-370,373. |
| |
| 作者姓名： | 杨开颜 |
| |
| 作者单位： | 温州医学院第一附属医院,病理科,浙江,温州,325000 |
| |
| 基金项目： | 温州市科技发展计划基金资助项目 (S2 0 0 1A2 9) |
| |
| 摘 要： | 目的 :研究p73基因与乳癌的关系。方法 :应用免疫组化、RT PCR等技术检测乳癌组织p73基因的表达情况。结果 :45例乳癌组织p73基因表达阳性者 2 1例 ,明显高于良性乳腺肿瘤 (P <0 .0 5) ;淋巴结转移阳性者p73基因表达明显高于阴性者 (P <0 .0 5)。结论 :p73基因表达增多可能与乳腺癌发病有关
|
| 关 键 词： | p73 腺癌 免疫组化 RT-PCR |
| 文章编号： | 1000-2138(2003)06-0369-03 |
Analysis of p73 gene in breast cancer |
| |
| YANG Kai-yan.Analysis of p73 gene in breast cancer[J].Journal of Wenzhou Medical College,2003,33(6):369-370,373. |
| |
| Authors: | YANG Kai-yan |
| |
| Institution: | YANG Kai-yan.Department of Pathology,the First Affiliated Hospital of Wen zhou Medical College,Wenzhou 325000 |
| |
| Abstract: | Objective:To investigate the relationship between p73 gene and breast cancer.Methods:The expression of p73 gene in breast cancer tissues wer e detected by immunohistochemical and RT-PCR. Results:The expression of p73 gene is significantly higher in b reast cancer(21/45) than in breast benign tumors(P<0.05);also i s significantly higher in positive metastasis of lymph nodes than in nagetive o nes(P<0.05). Conclusion:The increasing expression of p73 gene may be related with breast cancer. |
| |
| Keywords: | p73 breast cancer immunohischemical RT-PCR |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
