年龄与乳腺癌患者保乳术后局部复发风险的Meta分析

[目的]使用Meta分析方法分析年龄与乳腺癌患者保乳术后局部复发的关系。[方法]检索关于年龄与乳腺癌保乳术后具有复发关系的文献,采用Meta分析。[结果]共有5篇文献符合纳入标准,乳腺癌保乳术后患者5188例,其中＂年轻＂患者380例,＂年老＂患者4808例。Meta分析显示相对于＂年老＂患者,＂年轻＂患者术后局部复发风险增加（OR=3.73,95%CI：1.64～8.49）。以40岁为界限,≤40岁组术后局部复发风险增加（OR=4.10,95%CI：1.55～10.85）。[结论]＂年轻＂乳腺癌患者保乳术后局部复发风险增高,≤40岁患者局部复发明显高于〉40岁患者。

The Relationship between Age and Risk of Local Recurrence in Patients with Breast Cancer after Conserving Surgery

[Purpose] To evaluate the relationship between age and local recurrence in patients with breast cancer after conserving surgery by meta analysis.[Methods] The literature concerning the association between age and local recurrence was searched.A Meta analysis was performed.[Results] Five articles,including 5 188 patients were involved in this study.Of them there were 380 younger patients and 4 808 elder patients.Meta analysis showed that compared to elder patients,the risk of local recurrence in younger pati...