肠管破裂伤经海水浸泡后的水、电解质变化的实验研究

目的　分析开放性腹部损伤并肠管破裂伤合并海水浸泡后水、电解质和酸碱平衡的变化 ,为海战时开放性腹部损伤并肠管破裂伤的早期救治提供理论依据。方法　成年杂种犬 2 6只 ,制作开放性腹部损伤并肠管破裂伤动物模型。随机分为海水浸泡组 (海水组致伤后浸泡于人工海水 ,n =10 )、对照组 (致伤后不浸泡 ,n =10 )和生理盐水浸泡组 (生理盐水组 ,致伤后浸泡于生理盐水 ,n =6)。观察三组的水、电解质、酸碱平衡的变化规律 ,并进行对比分析。结果　海水组出现明显的水、电解质及酸碱平衡紊乱 ;对照组和生理盐水组水、电解质及酸碱平衡在致伤前后无明显变化。结论　海水浸泡是导致开放性腹部损伤并肠管破裂伤员体液代谢紊乱的主要因素

Experimental study of water and electrolyte changes following seawater immersion of animals with intestinal rupture

Objective To evaluate the changes in water, electrolyte and acid-base balance after seawater immersion in cases of open abdominal trauma associated with intestinal rupture, and to obtain a theoretical basis for the early treatment of open abdominal injury with intestinal rupture in naval combat. Methods A canine model of open abdominal trauma with intestinal rupture was established in 26 healthy adult dogs, and they were divided randomly into three groups. All animals were subjected to abdominal wall incision and intestinal rupture. Seawater immersion group(n=10) was immersed into artificial seawater after trauma; normal saline solution group(n=6) was immersed into normal saline solution after trauma; control group (n=10) had no immersion. The 3 groups were observed for changes in water, electrolyte and acid-base balance, and the results were analysed and compared. Results Signficant disturbance of water, electrolyte and acid-base imbalance were observed in the seawater immersion groups, but no significant changes of these parameters were seen in the control group and normal saline group. Conclusion Seawater immersion is the main factor leading to the disturbance of body metabolism after open abdominal trauma with intestinal rupture.