克山病发病和转归的动态分析

1973～1990年,对陕西省黄陵县店头病区克山病发病和转归进行了观察,结果表明:(l)1974年起,店头病区各型克山病发病率呈下降趋势,急性(包括急型和亚急型)、慢型和潜在型年平均下降率分别为75.2％、32.4%和28.6％,1983年至今未见急发病例,但慢型和潜在型仍有新发;(2)1974年后潜在型病情恶化率平均下降26.2％,1980年后新发慢型2～7年生存率明显提高;(3)慢型克山病病死率高,其5、10和15年病死率分别为70.9%、89.1%和93.6%,治疗慢型和管理潜在型是降低病死率的关键。

Dynamic Analysis of the Incidences and Outcome of Keshan Disease

A dynamic observation on the incidence rates and outcome of Keshan disease (KD) wasconducted in 2 communities in a heavily endemic area in Shaanxi province from 1973 to 1990. Results showed that:(l) From 1974, the annual incidence rates of acute (including subacute), chronic and latent KD were declining, with average decreasing rates of 75.2%, 32.4% and 28.6% respectively. No new cases of acute KD has been found since 1983, however, some new chronic and latent cases existed. (2) Since 1974, the annual deterioration rate of latent KD was also declining by 26.2%, and annual survival rate of newly occurred chronic KD elevated significantly from 1980. (3) Mortality rates of chronic KD were high, which were 70.9%,89.1% and 93.6% in the periods of 5, 10 and 15 years respectively. It is therefore very important to treat chronic and manage latent KD so as to decrease the mortality rate remarkably.