Glutathione metabolism in red cell aging |
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| Authors: | H Imanishi T Nakai T Abe T Takino |
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| Affiliation: | Third Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamikyo-Ku, Kyoto, 602 Japan |
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| Abstract: | Normal human red cells were centrifugally separated according to age by discontinuous density gradient of Percoll. Reduced glutathione (GSH), GSH stability and glucose-6-phosphate dehydrogenase (G6PD) activity in fractionated red cells decreased with age, while oxidized glutathione (GSSG) and methemoglobin (MetHb) increased with age. |
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| Keywords: | Reduced glutathione Oxidized glutathione Red cell aging |
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