| 人参根总皂甙对诱发遗传损伤的保护作用 |
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| 摘 要： | 本研究应用小鼠骨髓细胞姐妹染色单体互换（ＳＣＥ）试验，研究了人参根总皂甙（ＧＲＳ）的诱变性及对诱变剂造成遗传损伤的保护作用。结果证明，ＧＲＳ本身无诱变性，且对诱变剂诱发的小鼠骨髓细胞的ＳＣＥ值有明显的降低作用，即有抗诱变性。
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| 关 键 词： | 人参根总皂甙，姐妹染色单体互换，小鼠骨髓细胞，遗传损伤 |
Protective action of ginseng root saponins(GRS)on genetic damage |
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| Authors: | LuYao Xu Guizhen Wu
Guangheng |
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| Institution: | Dept.of Medical Genetics;* Dept.of Radiation Biology |
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| Abstract: | In this dissertation,the
protective action of GRS on genetic damage and it’s mutatiininduced by mutagens in marrow
cells of mice was studied by sister chromatid exchage (SCE)test.Theresults demonstrated that
GRS itself did not present mutation. And GRS showed an obvious reducingeffect on SCE induced
by mutagen in bone marrow cells of mice. |
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| Keywords: | ginseng root saponins(GRS) sister chromatid exchanges (SCE) mouse bone mar-row cells genetic damage |
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