绝经后无症状子宫内膜息肉潜在恶变相关危险因素分析

目的:分析绝经后无症状子宫内膜息肉患者发生潜在恶变相关危险因素。方法:选取本院2015年11月—2016年12月收治的绝经后无症状子宫内膜息肉患者120例为研究对象,按病理类型分为病变组(子宫内膜息肉伴非典型增生和子宫内膜息肉伴子宫内膜癌)、良性组(子宫内膜息肉和子宫内膜息肉伴单纯/复杂增生),每组各60例。对比两组患者的相关观察指标、息肉径线情况,并采用logistic回归分析绝经后无症状子宫内膜息肉患者发生潜在恶变及恶变的相关危险因素。结果:病变组患者的息肉径线≥15mm率、肥胖率均较良性组升高(P0.05);logistic多元回归分析发现,绝经后无症状子宫内膜息肉患者发生潜在恶变的危险因素为息肉径线≥15mm、肥胖(P0.05)。结论:绝经后无症状子宫内膜息肉患者发生潜在恶变及恶变与息肉径线≥15mm、肥胖有一定的关系。

Analysis of associated risk factors of potential malignant for patients with postmenopausal asymptomatic endometrial polyps

Objective:To analyze the related risk factors of potential malignant for patients with postmenopausal asymptomatic endometrial polyps.Methods:One hundred and twenty patients with postmenopausal asymptomatic en dometrial polyps who treated in the first people's hospital of Nantong city were selected as research subjects.According to pathological types,all the included patients were divided into precancerous lesions/malignant transformation group (patients had endometrial polyps with atypical hyperplasia or with endometrial cancer) and the benign group (patients had endometrial polyps only or with simple/complex hyperplasia),60 cases in each group.The relevant indicators and polyp diameter of patients were compared between the two groups,and logistic regression analysis was used to analyze the related risk factors of potential malignant for patients with postmenopausal asymptomatic endometrial polyps.Results:The rates of polyp diameter ≥15mm,obesity,polyp diameter ≥20mm,and polyp diameter 15-19mm of patients in the precancerous lesions/malignant group were significantly higher than those of patients in the benign group,which had statistical significant difference (P＜0.05).The indicators,such as obesity,hypertension,diabetes and polyp diameter ≥ 15mm were analyzed by multiple logistic regression.The result showed that polyp diameter≥15mm and obesity were the risk factors of potential malignant for patients with postmenopausal asymptomatic endometrial polyps (P＜0.05).Conclusions:Polyp diameter≥15mm and obesity are correlated with potential malignant or malignant of patients with postmenopausal asymptomatic endometrial polyps.