急性胰腺炎患者检测血清PCT和CRP的临床意义

目的]探讨急性胰腺炎患者检测血清降钙素原（PCT）和C-反应蛋白（CRP）水平的临床意义.方法]选择86例急性胰腺炎患者,其中轻症急性胰腺炎（MAP）47例,重症急性胰腺炎（SAP） 39例,另选择35例健康体检者作为对照组.分别对急性胰腺炎患者及对照组进行血清PCT和CRP水平测定.结果]MAP组和SAP组患者血清PCT及CRP水平均高于对照组（均P＜0.05）,SAP组患者同期PCT及CRP水平均高于MAP组（均P＜0.05）.结论]监测血清PCT和CRP水平对急性胰腺炎患者病情严重程度和预后的评估具有重要的临床意义.

Detection of serum PCT and C-reactive protein in patients with severe acute pancreatitis and their clinical significance

Objective]To investigate the clinical significance of serum procalcitonin（PCT）and C-reactive protein（CRP）detected in patients with acute pancreatitis.Methods]Eighty-six cases of acute pancreatitis were enrolled,47 cases with mild acute pancreatitis（MAP）and 39 cases with severe acute pancreatitis （SAP）.Thirty-five cases of healthy people were chosen as a control group.The levels of serum PCT and CRP were measured.Results]The levels of serum PCT and CRP in acute pancreatitis patients were significantly higher than those of control group（all P＜0.05）,PCT and CRP levels in patients with SAP group were higher than those in the same period of MAP group（all P＜0.05）.Conclusion]Monitoring of serum PCT and CRP levels has important clinical significance to detect severity and prognosis in patients with acute pancreatitis disease.