| 大鼠心房后壁NA,Ach及SS含量对心率的影响 |
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| 引用本文： | 李玉明 殷树仪. 大鼠心房后壁NA,Ach及SS含量对心率的影响[J]. 滨州医学院学报, 1999, 22(4): 313-315 |
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| 作者姓名： | 李玉明 殷树仪 |
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| 作者单位： | [1]滨州医学院附属医院外科 [2]同济医科大学 |
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| 摘 要： | 目的 探讨去甲肾上腺素（ＮＡ）、乙酰胆碱（Ａｃｈ０及生长抑素（ＳＳ）含量对大鼠心率的影响。方法 用６－ＯＨ－ＤＡ（５０ｍｇ／ｋｇ）经尾静脉注射，作心电图，然后用生化测定方法观察大鼠心房后壁ＮＡ、ＳＳ含量及ＡｃｈＥ活性的变化。方法：实验组大鼠心房后壁ＮＡ含量明显降低，ＳＳ含量及ＡｃｈＥ活性明显升高。进一步数理统计结果显示，心率与ＮＡ、ＳＳ含量及ＡｃｈＥ活性均密切相关，且ＳＳ含量与ＡｃｈＥ活性的阳性极
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| 关 键 词： | 去甲肾上腺素 乙酰胆碱 生长抑素 逐步回归 心率 |
EFFECTS ON HEART RATE OF NA,ACH AND SS LEVEL IN POSTWALL OF RAT HEART |
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| LiYuming,YinShuyi,WangJianben. EFFECTS ON HEART RATE OF NA,ACH AND SS LEVEL IN POSTWALL OF RAT HEART[J]. Journal of Binzhou Medical College, 1999, 22(4): 313-315 |
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| Authors: | LiYuming YinShuyi WangJianben |
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| Affiliation: | LiYuming1,YinShuyi2,WangJianben2 |
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| Abstract: | Objective: TostudytheeffcetsofNA,AchandSSlevelsonheartrateofrat. Methods: ECGwasrecorded,NA,SSlevelandAchEactivitywereobservedbybiochemicalmethodsafter6OHDA(50mg/kg)hadbeeninjectedthroughcaudalveins. Results:WTBZInexperimentalgroup,amarkedreductionofNAlevelandsignificantincreaseofAchEactivityandSSlevelinpostwallofratheartwerefound.MathematicalstatisticsdemonstratedthatHRwasintimatelycorrelatedwithNA,SSlevelandAchEactivity.SSwasextremelycorrelatedwithAchEactivity. Conclusion: SS isanimportantregulatingpeptideincardiacneuralstructures,itseffectonHRissimilartoAch;Thereis reciprocalinhibitoryactionbetweencardiacsympatheticandparasympatheticnevers,andsympatheticnerveactsprominentlyinnormalcondition. |
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| Keywords: | noradrenaline(NA) acetylcholine(Ach) somatostatin(SS) stepwiseregression heartrate |
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