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肿瘤MR全身弥散加权成像与PET成像初步对比
引用本文:康厚艺,张伟国,金榕兵,王毅,陈金华,张乐天,汪黎黎,邹博,马长锁. 肿瘤MR全身弥散加权成像与PET成像初步对比[J]. 中国医学影像技术, 2010, 26(4): 748-751
作者姓名:康厚艺  张伟国  金榕兵  王毅  陈金华  张乐天  汪黎黎  邹博  马长锁
作者单位:1. 第三军医大学第三附属医院野战外科研究所放射科,重庆,400042
2. 第三军医大学第三附属医院野战外科研究所核医学科,重庆,400042
摘    要:目的 通过与PET成像比较,探讨MR全身弥散加权成像(WB-DWI)在肿瘤诊断中的应用价值. 方法 采用1.5T MR对22例临床高度怀疑为恶性肿瘤并已完成PET检查的患者行WB-DWI扫描,比较两种成像方法对病变显示的差异以及病变的ADC值与SUV值相关性. 结果 WB-DWI所见病灶数目多于PET检查,两种方法检出的肺、纵隔及腹部病灶数差异无统计学意义(P>0.05),WB-DWI检出骨的病灶数多于PET检查,差异有统计学意义(P<0.05).两种方法检出病灶的部位大多数一致.病变的ADC值与SUV值无相关性. 结论 与PET成像相比较,WB-DWI显示的肿瘤病灶数量较多,对成人转移性骨肿瘤的显示敏感性高于PET,可作为肿瘤全身筛查的一种补充方法.

关 键 词:磁共振成像  弥散加权成像  正电子发射断层摄影  肿瘤
收稿时间:2009-06-16
修稿时间:2010-03-02

Preliminary comparison of whole-body diffusion-weighted MRI and PET on tumor imaging
KANG Hou-yi,ZHANG Wei-guo,JIN Rong-bin,WANG Yi,CHEN Jin-hu,ZHANG Le-tian,WANG Li-li,ZOU Bo and MA Chang-suo. Preliminary comparison of whole-body diffusion-weighted MRI and PET on tumor imaging[J]. Chinese Journal of Medical Imaging Technology, 2010, 26(4): 748-751
Authors:KANG Hou-yi  ZHANG Wei-guo  JIN Rong-bin  WANG Yi  CHEN Jin-hu  ZHANG Le-tian  WANG Li-li  ZOU Bo  MA Chang-suo
Affiliation:Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Nuclear Medicine, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China;Department of Radiology, Third Affiliated Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
Abstract:Objective To assess the value of clinical applications of whole-body diffusion-weighted imaging (WB-DWI) in diagnosing patients with malignant tumors compared with positron emission tomography (PET). Methods A total of 22 patients with highly suspected malignant tumors underwent WB-DWI after PET. The differences between the two imaging methods were compared in displaying lesions, and the correlation between ADC and SUV value was analyzed. Results More lesions were showed with WB-DWI than PET. There was no significant difference between the two methods in detecting the lesions of lung, mediastinal septum or abdomen (P>0.05), but more lesions in skeleton were showed with WB-DWI (P<0.05). No significant correlation between ADC and SUV value was found. Conclusion Compared with PET, WB-DWI can detect more tumor lesions. The sensitivity of WB-DWI in detecting metastatic tumors of bone is higher than that of PET.
Keywords:Magnetic resonance imaging  Diffusion-weighted imaging  Positron-emission tomography  Neoplasms
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