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Transcription and DNA Methylation Patterns of Blood-Derived CD8+ T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis |
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| Authors: | Marco Gasparetto Felicity Payne Komal Nayak Judith Kraiczy Claire Glemas Yosef Philip-McKenzie Alexander Ross Rachel D. Edgar Daniel R. Zerbino Camilla Salvestrini Franco Torrente Nicholas T. Ventham Rahul Kalla Jack Satsangi Peter Sarkies Robert Heuschkel Matthias Zilbauer |
| Affiliation: | 1. Department of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, Cambridge, United Kingdom;2. Department of Paediatric Gastroenterology, Hepatology and Nutrition, Cambridge University Hospitals, Addenbrooke’s, Cambridge, United Kingdom;3. Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom;4. European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom;5. Academic Coloproctology, Western General Hospital, Edinburgh, Edinburgh, United Kingdom;6. Medical Research Council Centre for Inflammation Research, Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom;7. Translational Gastroenterology Unit, University of Oxford, Oxford, United Kingdom;8. Medical Research Council London Institute of Medical Sciences, United Kingdom;8. Institute of Clinical Sciences, Imperial College London, United Kingdom |
| Abstract: |  |
| Keywords: | Epigenetic Prognosis Biomarker Validation CD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" Crohn’s disease IBD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" inflammatory bowel disease UC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" ulcerative colitis WGCNA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" weighted gene co-expression network analysis |
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