Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production
Authors: Yuta Myojin Hayato Hikita Masaya Sugiyama Yoichi Sasaki Kenji Fukumoto Sadatsugu Sakane Yuki Makino Nobuyuki Takemura Ryoko Yamada Minoru Shigekawa Takahiro Kodama Ryotaro Sakamori Shogo Kobayashi Tomohide Tatsumi Hiroshi Suemizu Hidetoshi Eguchi Norihiro Kokudo Masashi Mizokami Tetsuo Takehara
Affiliation: 1. Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan;2. Genome Medical Sciences Project, National Center for Global Health and Medicine, Ichikawa, Japan;3. Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan;4. Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan;5. Department of Laboratory Animal Research, Central Institute for Experimental Animals
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Keywords: Liver Cancer Cell–Cell Interaction ASMA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0025" }," $$" :[{" #name" :" text" ," _" :" α–smooth muscle actin CRISPR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" clustered regularly interspaced short palindromic repeats GDF15" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" growth differentiation factor 15 GFAP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" glial fibrillary acidic protein GFRAL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" glial cell-derived neurotrophic factor receptor alpha-like HCC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" hepatocellular carcinoma HSC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" hepatic stellate cell IRB" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" Institutional Review Board KO" },{" #name" :" keyword" ," $" :{" id" :" kwrd0105" }," $$" :[{" #name" :" text" ," _" :" knockout LRAT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0115" }," $$" :[{" #name" :" text" ," _" :" lectin: retinol acyltransferase NOG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0125" }," $$" :[{" #name" :" text" ," $$" :[{" #name" :" italic" ," _" :" NOD/Shi-scid/IL-2Rγ (null) scRNAseq" },{" #name" :" keyword" ," $" :{" id" :" kwrd0135" }," $$" :[{" #name" :" text" ," _" :" single-cell RNA sequencing WT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0145" }," $$" :[{" #name" :" text" ," _" :" wild-type
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