STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD |
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| Authors: | Dan Turner Amanda Ricciuto Ayanna Lewis Ferdinando D’Amico Jasbir Dhaliwal Anne M. Griffiths Dominik Bettenworth William J. Sandborn Bruce E. Sands Walter Reinisch Jürgen Schölmerich Willem Bemelman Silvio Danese Jean Yves Mary David Rubin Jean-Frederic Colombel Laurent Peyrin-Biroulet Iris Dotan Axel Dignass |
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| Affiliation: | 1. Shaare Zedek Medical Center, the Hebrew University of Jerusalem, Jerusalem, Israel;2. Hospital for Sick Children, Toronto, Canada;3. Division of Gastroenterology, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida;4. Humanitas Clinical and Research Center – IRCCS, Rozzano and Humanitas University, Department of Biomedical Sciences, Pieve Emanuele, Milan, Italy;5. Cincinnati Children’s Hospital, University of Cincinnati, Cincinnati, Ohio;6. Department of Medicine B for Gastroenterology and Hepatology, University Hospital Münster, Münster, Germany;7. Division of Gastroenterology, University of California San Diego, La Jolla, California;8. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York;9. Medical University of Vienna, Department of Internal Medicine III, Division Gastroenterology and Hepatology, Vienna, Austria;10. (Private Practice), Hofheim, Germany;11. Department of Surgery, Amsterdam UMC, University of Amsterdam, Locatie AMC, the Netherlands;12. Inserm UMR1153 CRESS, équipe ECSTRRA, Université de Paris, Paris, France;13. Section of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, Illinois;14. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York;15. Department of Gastroenterology and Inserm NGERE U1256, University Hospital of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France;16. Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;17. Department of Medicine I, Agaplesion Markus Hospital, Goethe University, Frankfurt/Main, Germany;1. Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan;2. IBD Center, Sapporo Kosei General Hospital, Sapporo, Japan;3. Department of Inflammatory Bowel Disease, Hyogo College of Medicine, Nishinomiya, Japan;4. IBD Center, Yokkaichi Hazu Medical Center, Yokkaichi, Japan;5. Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan;6. Advanced Research Institute, Tokyo Medical and Dental University, Tokyo, Japan;7. Department of Endoscopy and Medicine, Hiroshima University Hospital, Hiroshima, Japan;8. Department of Gastroenterology and Hepatology, Kyorin University School of Medicine, Mitaka, Japan;9. Department of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, Japan;10. Department of Gastroenterology, Sapporo Medical College, Sapporo, Japan;11. Center for Inflammatory Bowel Disease, Division of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan;12. Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan;13. Department of Pathology, Hirosaki Municipal Hospital, Hirosaki, Japan;14. Department of Data Science, Yokohama City University, Yokohama, Japan;15. Clinical and Translational Research Centre, Keio University School of Medicine, Tokyo, Japan;p. Department of Internal Medicine, Toho University Sakura Medical Center, Sakura, Japan;1. Institute of Immunology and Immunotherapy, NIHR Wellcome Trust Clinical Research Facilities, University of Birmingham, and University Hospitals Birmingham NHS Trust, Birmingham, United Kingdom;2. National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Birmingham, United Kingdom;3. Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Canada;4. Institute for Biological Physics, University of Cologne, Cologne, Germany;5. Division of Gastroenterology, Queen Alexandra Hospital, Portsmouth, United Kingdom;6. Department of Gastroenterology, Spedali Civili, Brescia, Italy;7. Division of Gastroenterology, University of Torino, Torino, Italy;8. Division of Gastroenterology, Klinikum Böblingen, Germany;9. Division of Gastroenterology, University of Washington, Seattle, Washington;10. Division of Gastroenterology, Kings College London, London, United Kingdom;11. Division of Gastroenterology, University Hospitals Leuven, Belgium;12. Division of Gastroenterology, Johns Hopkins Hospital, Baltimore, Maryland;13. Division of Gastroenterology, Peking Union Medical College Hospital, Beijing, China;14. Division of Gastroenterology, University of Nottingham, Nottingham, United Kingdom;15. Division of Gastroenterology, IRCCS Policlinico San Donato, Milan, Italy;16. Division of Gastroenterology, University of Erlangen, Erlangen, Germany;17. Division of Gastroenterology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy;18. Klinikum Bayreuth, Bayreuth, Germany;19. Institute of Pathology, Spedali Civili, Brescia, Italy;20. Division of Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom;21. Helios HSK Wiesbaden, Wiesbaden, Germany;1. Department of Gastroenterology and INSERM NGERE U1256, Nancy University Hospital, University of Lorraine, Vandoeuvre-lès-Nancy, France;2. Department of Radiology, Nancy University Hospital, University of Lorraine, Vandoeuvre-lès-Nancy, France;3. Department of Gastroenterology, University Hospital of Limoges Dupuytren, Limoges, France;4. Department of Gastroenterology, University Hospital of Marseille Nord, University of Aix-Marseille, Marseille, France;5. IBD Center, Department of Gastroenterology, Humanitas Clinical and Research Center, IRCCS, Rozzano, Milan, Italy;6. Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy;1. Department of Gastroenterology, Icahn School of Medicine, New York, New York;2. Division of Gastroenterology, Department of Medicine and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada;3. Institut National de la Santé et de la Recherche Médicale U954 and Department of Gastroenterology, Nancy University Hospital, Lorraine University, France;1. University Hospital Gasthuisberg, Leuven, Belgium;2. Janssen Research & Development, LLC, Spring House, Pennsylvania;3. The Dr Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York;4. Atlanta Gastroenterology Associates, Atlanta, Georgia;5. Robarts Clinical Trials, Robarts Research Institute, Western University, London, Ontario, Canada;6. University of California San Diego, La Jolla, California |
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| Abstract: | |
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| Keywords: | Treat-to-Target Endoscopic Healing Biologics Patient-Reported Outcomes Biomarkers AUC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" area under the curve CD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0050" }," $$" :[{" #name" :" text" ," _" :" Crohn’s disease CDAI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0060" }," $$" :[{" #name" :" text" ," _" :" Crohn’s disease activity index CRP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0070" }," $$" :[{" #name" :" text" ," _" :" C-reactive protein EH" },{" #name" :" keyword" ," $" :{" id" :" kwrd0080" }," $$" :[{" #name" :" text" ," _" :" endoscopic healing ESR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0090" }," $$" :[{" #name" :" text" ," _" :" erythrocyte sedimentation rate FC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0100" }," $$" :[{" #name" :" text" ," _" :" fecal calprotectin IBD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0110" }," $$" :[{" #name" :" text" ," _" :" inflammatory bowel diseases IOIBD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0120" }," $$" :[{" #name" :" text" ," _" :" International Organization for the Study of Inflammatory Bowel Disease MES" },{" #name" :" keyword" ," $" :{" id" :" kwrd0130" }," $$" :[{" #name" :" text" ," _" :" Mayo endoscopic subscore PRO" },{" #name" :" keyword" ," $" :{" id" :" kwrd0140" }," $$" :[{" #name" :" text" ," _" :" patient-reported outcome QoL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0150" }," $$" :[{" #name" :" text" ," _" :" quality of life SF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0160" }," $$" :[{" #name" :" text" ," _" :" stool frequency STRIDE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0170" }," $$" :[{" #name" :" text" ," _" :" Selecting Therapeutic Targets in IBD TNF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0180" }," $$" :[{" #name" :" text" ," _" :" tumor necrosis factor UC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0190" }," $$" :[{" #name" :" text" ," _" :" ulcerative colitis |
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