Efficacy and Safety of Aldafermin,an Engineered FGF19 Analog,in a Randomized,Double-Blind,Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Efficacy and Safety of Aldafermin,an Engineered FGF19 Analog,in a Randomized,Double-Blind,Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis

Authors:	Stephen A Harrison Guy Neff Cynthia D Guy Mustafa R Bashir Angelo H Paredes Juan P Frias Ziad Younes James F Trotter Nadege T Gunn Sam E Moussa Anita Kohli Kristin Nelson Mildred Gottwald William CG Chang Andrew Z Yan Alex M DePaoli Lei Ling Hsiao D Lieu

Institution:	1. Radcliffe Department of Medicine, University of Oxford, United Kingdom;2. Pinnacle Clinical Research, San Antonio, Texas;3. Covenant Research, Sarasota, Florida;4. Pathology, Duke University, Durham, North Carolina;5. Radiology and Medicine (Gastroenterology), Duke University, Durham, North Carolina;6. San Antonio Military Medical Center, San Antonio, Texas;7. National Research Institute, Los Angeles, California;8. Gastro One Research, Germantown, Tennessee;9. Clinical Research and Education, Texas Digestive Disease Consultants, Dallas, Texas;10. Pinnacle Clinical Research, Austin, Texas;11. Adobe Clinical Research, Tucson, Arizona;12. Arizona Liver Health, Chandler, Arizona;13. NGM Biopharmaceuticals, South San Francisco, California

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Keywords:	Nonalcoholic Fatty Liver Disease NAFLD Metabolism Lipid ALT"} {"#name":"keyword" "$":{"id":"kwrd0035"} "$$":[{"#name":"text" "_":"alanine aminotransferase AST"} {"#name":"keyword" "$":{"id":"kwrd0045"} "$$":[{"#name":"text" "_":"aspartate aminotransferase C4"} {"#name":"keyword" "$":{"id":"kwrd0055"} "$$":[{"#name":"text" "_":"7alpha-hydroxy-4-cholesten-3-one CI"} {"#name":"keyword" "$":{"id":"kwrd0065"} "$$":[{"#name":"text" "_":"confidence interval ELF"} {"#name":"keyword" "$":{"id":"kwrd0075"} "$$":[{"#name":"text" "_":"enhanced liver fibrosis FGF19"} {"#name":"keyword" "$":{"id":"kwrd0085"} "$$":[{"#name":"text" "_":"fibroblast growth factor 19 LDL-C"} {"#name":"keyword" "$":{"id":"kwrd0095"} "$$":[{"#name":"text" "_":"low-density lipoprotein cholesterol LFC"} {"#name":"keyword" "$":{"id":"kwrd0105"} "$$":[{"#name":"text" "_":"liver fat content LS"} {"#name":"keyword" "$":{"id":"kwrd0115"} "$$":[{"#name":"text" "_":"least-squares MRI-PDFF"} {"#name":"keyword" "$":{"id":"kwrd0125"} "$$":[{"#name":"text" "_":"magnetic resonance imaging-proton density fat fraction NAS"} {"#name":"keyword" "$":{"id":"kwrd0135"} "$$":[{"#name":"text" "_":"Nonalcoholic Fatty Liver Disease Activity Score NASH CRN"} {"#name":"keyword" "$":{"id":"kwrd0145"} "$$":[{"#name":"text" "_":"Nonalcoholic Steatohepatitis Clinical Research Network PIIINP"} {"#name":"keyword" "$":{"id":"kwrd0155"} "$$":[{"#name":"text" "_":"N-terminal pro-peptide of type III collagen Pro-C3"} {"#name":"keyword" "$":{"id":"kwrd0165"} "$$":[{"#name":"text" "_":"neoepitope-specific N-terminal pro-peptide of type III collagen
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