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Clinico-immunological profile in a case of hepatic tubercular abscess: A rare manifestation of extrapulmonary TB in an immunocompetent child
Authors:Bineeta Kashyap  Neha Gupta  Krishna Singha  Pooja Dewan  Puneeta Hyanki  Narendra Pal Singh  Ashwani Khanna
Institution:1. Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi 110095, India;2. Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi 110095, India;3. CMO I/C, DOTS Center, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi 110095, India;4. RNTCP, New Delhi 110011, India
Abstract:Tubercular liver abscess is a rare entity even in an endemic area for TB. We report here a rare case of pediatric tuberculous liver abscess, the etiology of which was established using recently introduced Cartridge based nucleic acid amplification test (CBNAAT). A 7 years old male child presented with vomiting, pain abdomen and fever. Hepatomegaly was found on examination. Ultrasound of abdomen revealed two liver abscesses in the right lobe. Patient remained symptomatic even after empirical antimicrobial therapy. On diagnostic tap Gram stained smear of the pus showed polymorphs with negative culture. CBNAAT was positive for Mycobacterial tuberculosis and sensitive to rifampicin. Subjecting difficult extrapulmonary specimens to relevant microbiological investigations along with CBNAAT and other newer methods may improve diagnosis of tuberculosis in such rare cases thus leading to an early management and decrease in morbidity.
Keywords:Tuberculosis  Liver abscess  CBNAAT  Pediatric  Immunocompetent
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