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Mucosal Genomics Implicate Lymphocyte Activation and Lipid Metabolism in Refractory Environmental Enteric Dysfunction
Authors:Yael Haberman  Najeeha T. Iqbal  Sudhir Ghandikota  Indika Mallawaarachchi  Phillip J. Dexheimer  Najeeb Rahman  Rotem Hadar  Kamran Sadiq  Zubair Ahmad  Romana Idress  Junaid Iqbal  Sheraz Ahmed  Aneeta Hotwani  Fayyaz Umrani  Lubaina Ehsan  Greg Medlock  Sana Syed  Lee A. Denson
Affiliation:1. Department of Pediatrics, Cincinnati Children’s Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio;2. Department of Pediatrics, Sheba Medical Center, Tel-HaShomer, affiliated with the Tel-Aviv University, Israel;3. Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan;4. Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan;5. Division of Biomedical Informatics, Cincinnati Children''s Hospital Medical Center Cincinnati, Department of Computer Science, University of Cincinnati College of Engineering, Cincinnati, Ohio;6. Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia;7. Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan;8. Department of Pediatrics, University of Virginia, Charlottesville, Virginia
Abstract:
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  • Keywords:Anthropometrics  DNA Methylation  RNA Sequencing  Intestine  AKU"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0035"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Aga Khan University  CRFs"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0045"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  conditional random forests  Ctl"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  control  DMRs"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  differentially methylated regions  DNAm"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  DNA methylation  EED"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  environmental enteric dysfunction  FDR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  false discovery rate  HAZ"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  $$"  :[{"  #name"  :"  __text__"  ,"  _"  :"  length/height-for-age "  },{"  #name"  :"  italic"  ,"  _"  :"  z"  },{"  #name"  :"  __text__"  ,"  _"  :"   score  IFNG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0115"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  interferon gamma  IGF"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0125"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  insulin-like growth factor  mRNAseq"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0135"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  messenger RNA  rDMR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0145"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  regulatory DMR  SEEM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0155"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Study of Environmental Enteropathy and Malnutrition  WAZ"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0165"  },"  $$"  :[{"  #name"  :"  text"  ,"  $$"  :[{"  #name"  :"  __text__"  ,"  _"  :"  weight-for-age "  },{"  #name"  :"  italic"  ,"  _"  :"  z"  },{"  #name"  :"  __text__"  ,"  _"  :"   score  WHZ"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0175"  },"  $$"  :[{"  #name"  :"  text"  ,"  $$"  :[{"  #name"  :"  __text__"  ,"  _"  :"  weight-for- length/height "  },{"  #name"  :"  italic"  ,"  _"  :"  z"  },{"  #name"  :"  __text__"  ,"  _"  :"   score  WGCNA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0185"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  weighted gene coexpression network analysis
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