| NDV-ATV对肿瘤患者术后免疫功能的影响 |
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| 引用本文： | 曾冬竹,余佩武,蔡志民,石彦,王自强,吴淼,周立新. NDV-ATV对肿瘤患者术后免疫功能的影响[J]. 重庆医学, 2003, 32(7): 883-884 |
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| 作者姓名： | 曾冬竹 余佩武 蔡志民 石彦 王自强 吴淼 周立新 |
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| 作者单位： | 第三军医大学西南医院普通外科,重庆,400038 |
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| 摘 要： | 目的 探讨肿瘤患者术后NDV ATV治疗对免疫功能的影响。方法 采用流式细胞仪分析 115例术后接受NDV ATV治疗的肿瘤患者外周静脉血T淋巴细胞亚群及NK细胞的变化情况 ,并以 4 2例术后未接受NDV ATV治疗的肿瘤患者作为对照。结果 接受NDV ATV治疗的肿瘤患者 ,术后外周血中CD3+ 、CD4 + 所占比率、NK细胞活性和CD4 + /CD8+ 均较治疗前显著增高 (P<0 0 1) ,且明显高于未接受NDV ATV治疗的手术对照组患者 (P <0 0 5 )。结论 NDV ATV能改善肿瘤患者术后机体的免疫功能
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| 关 键 词： | 新城鸡瘟病毒修饰的自体肿瘤疫苗 T淋巴细胞 自然杀伤细胞 |
| 文章编号： | 1671-8348(2003)07-0883-02 |
The effect of immune function for tumor patient with NDV-ATV treatment after operation |
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| ZENG Dong zhu,YU Pei wu,CAI Zhi min,et al.. The effect of immune function for tumor patient with NDV-ATV treatment after operation[J]. Chongqing Medical Journal, 2003, 32(7): 883-884 |
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| Authors: | ZENG Dong zhu YU Pei wu CAI Zhi min et al. |
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| Abstract: | Objective To discuss the effect of immune function for tumor patient with NDV ATV(new castle disease virus modified autolgous tumor vaccine)treatment after operation.Methods T lymphocyte subsets and NK cell in peripheral venous blood of 115 tumor patients who accepted NDV ATV treatment were analysed by flow cytometer after operation.42 patients without NDV ATV treatment were used as control.Results The amount of CD3 +?CD4 +?NK and CD4 +/CD8 + were significantly increased after NDV ATV treatment ( P <0 01),moreover,which remarkablely higher that those didn't treat with NDV ATV( P <0 05).Conclusion NDV ATV can improve patient's immune function after operation. |
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| Keywords: | new castle disease virus modified autolgous tumor vaccine(NOV ATV) T lymphocyte subsets natural killer cells |
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