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BCG immunotherapy: be cautious of granulomas. Disseminated BCG infection and mycotic aneurysm as late complications of intravesical BCG instillations
Authors:Kamphuis J T  Buiting A G  Miseré J F  van Berge Henegouwen D P  van Soolingen D  Rensma P L
Institution:Department of Internal Medicine, St. Elisabeth Hospital, P.O. Box 90151, 5000 LC Tilburg, The Netherlands. interezt@wxs.nl
Abstract:We describe a 65-year-old man with a granulomatous hepatitis and a progressive mycotic aneurysm of the abdominal aorta. One year before he received intravesical bacillus Calmette--Guérin (BCG) for carcinoma of the bladder without any complaints. Only post-mortem investigations could confirm that he suffered from a systemic BCG infection. Literature is reviewed for this rare complication.
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