| 温和灸对自然衰老模型大鼠肝组织Rb、P53、Bcl-2、PKC表达的影响 |
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| 引用本文： | 谭琳蓥,赵天平,国兰琴,赵琛,刘慧荣,朱慧华,崔云华. 温和灸对自然衰老模型大鼠肝组织Rb、P53、Bcl-2、PKC表达的影响[J]. 环球中医药, 2011, 4(6): 406-412. DOI: 10.3969/j.issn.1674-1749.2011.06.002 |
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| 作者姓名： | 谭琳蓥 赵天平 国兰琴 赵琛 刘慧荣 朱慧华 崔云华 |
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| 作者单位： | 1. 上海中医药大学,201203
2. 201203, |
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| 基金项目： | 国家重点基础研究发展计划(973计划)(2009CB522900); 上海市重点学科建设项目(S30304) |
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| 摘 要： | 目的 研究温和灸对自然衰老大鼠肝组织Rb、P53、Bcl-2、PKC蛋白及其mRNA表达的影响.方法 24只SD大鼠随机分为正常组、自然衰老组、艾灸组.正常饲养20个月,待其自然进入衰老期以制备自然衰老大鼠模型,温和灸自然衰老大鼠双侧肾俞穴对其进行干预.应用原位杂交、免疫组化方法检测各组大鼠肝组织Rb、P53、Bcl-...
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| 关 键 词： | 艾灸 衰老 Rb P53 Bcl-2 蛋白激酶C |
Effect of warm moxibustion on the expression of Rb,P |
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| TAN Lin-ying,ZHAO Tian-ping,GUO Lan-qin,et al.. Effect of warm moxibustion on the expression of Rb,P[J]. Global Chinese Medicine, 2011, 4(6): 406-412. DOI: 10.3969/j.issn.1674-1749.2011.06.002 |
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| Authors: | TAN Lin-ying ZHAO Tian-ping GUO Lan-qin et al. |
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| Affiliation: | TAN Lin-ying,ZHAO Tian-ping,GUO Lan-qin,et al.Shanghai University of TCM,Shanghai 201203,China |
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| Abstract: | Objective To explore the effect of warm moxibustion on the expression of Rb,P53,Bcl-2 and PKC in liver tissue of natural aging rats.Methods 24 SD rats were randomly assigned into normal group,natural aging group and warm moxibustion group.The model of natural aging rats was established by being normally bred for twenty months.The rats in warm moxibustion were treated by warm moxibustion at Shenshu.The expression of Rb,P53,Bcl-2 and PKC was measured by in situ hybridization and immunohistochemistry.Results C... |
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| Keywords: | Moxibustion Aging Rb P53 Bcl-2 PKC |
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