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前列腺特异性抗原密度的测定在诊断前列腺癌中的价值
引用本文:徐耀庭,陈修诚,刘纯. 前列腺特异性抗原密度的测定在诊断前列腺癌中的价值[J]. 中华泌尿外科杂志, 1994, 0(3)
作者姓名:徐耀庭  陈修诚  刘纯
作者单位:兰州医学院附属第一医院泌尿外科
摘    要:对10例非转移性前列腺癌和20例前列腺增生的前列腺特异性抗原密度(PSAD)进行研究。前列腺癌平均PSAD值为0.711,而前列腺增生为0.075;两者有极显著性差异(P<0.001)。9例PSAD>0.2者,8例为前列腺癌。16例PSAD<0.1者,无1例前列腺癌。8例前列腺癌患者中有3例前列腺特异性抗原(PSA)<10ng/ml,1例<2.8ng/ml。16例前列腺增生患者中7例PSA>2.8ng/ml,3例>10ng/ml。表明血清PSA轻中度增高或正常时,PSAD可作为前列腺癌早期筛选诊断的有效指标之一。

关 键 词:前列腺,癌,抗原

Diagnostic value of prostate specific antigen density in prostate cancer
Xu yao-ting,Chen Xiu-cheng,Liu chun. Diagnostic value of prostate specific antigen density in prostate cancer[J]. Chinese Journal of Urology, 1994, 0(3)
Authors:Xu yao-ting  Chen Xiu-cheng  Liu chun
Abstract:Prostate specific antigen desity (PSAD)was studied in 10 cases of non-metastatic prostate cancer and 200cases of BPH.The mean PSAD values for prostate cancer and BPH were 0. 711 and 0. 075 respectively(P<0. 001). 8 out of 9 patients with PSAD greater than 0.2 had prostate cancer, in which 3 had a PSA less than 10ng/ml and 1 below 2. 8 ng/ml. In contrast. none of the 16 patients with PSAD less than 0. 1 had prostate cancer.Furthermore,7 out of 16 BPH patients were found to have a PSA greater than 2. 8 ng/ml and another 3 greater than 10ng/ml.these results showed that PSAD might be an effective indicator in screening early prostate cancer when the serum PSA has been moderately elevated or normal.
Keywords:Prostatic Carcinoma  
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