| 热毒宁注射液治疗小儿轮状病毒性肠炎的系统评价 |
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| 引用本文： | 方宝霞,陈富超,时晓亚,林洁. 热毒宁注射液治疗小儿轮状病毒性肠炎的系统评价[J]. 现代中西医结合杂志, 2011, 20(17): 2086-2087,2090 |
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| 作者姓名： | 方宝霞 陈富超 时晓亚 林洁 |
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| 作者单位： | 湖北医药学院附属东风医院,湖北,十堰,442008 |
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| 摘 要： | 目的评价热毒宁注射液治疗小儿轮状病毒性肠炎的临床疗效及安全性。方法计算机检索万方、维普数据库,收集热毒宁注射液治疗小儿轮状病毒性肠炎的随机对照研究,对符合纳入标准的研究进行M eta分析。结果检索到相关文献11篇,共1 528例患者。8项研究中热毒宁注射液组疗效(96.03%)优于利巴韦林注射液组(84.77%),综合检验Z=6.23,OR合并值3.67(95%C I为2.44~5.53),P<0.01;3项研究中热毒宁注射液+基础药物治疗组有效率(90.77%)明显高于基础药物对照组(62.56%),综合检验Z=6.60,OR合并值4.88(95%C I为3.05~7.81),P<0.01。结论热毒宁注射液治疗小儿轮状病毒性肠炎的临床疗效显著优于利巴韦林,且无明显不良反应。但由于目前的临床研究质量较低,尚需进行严格的、多中心的随机双盲对照研究加以证实。
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| 关 键 词： | 热毒宁注射液 轮状病毒性肠炎 系统评价 Meta分析 |
Systematic review of Reduning injection on infantile rotaviral enteritis |
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| Fang Baoxia,Chen Fuchao,Shi Xiaoya,Lin Jie. Systematic review of Reduning injection on infantile rotaviral enteritis[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2011, 20(17): 2086-2087,2090 |
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| Authors: | Fang Baoxia Chen Fuchao Shi Xiaoya Lin Jie |
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| Affiliation: | Fang Baoxia,Chen Fuchao,Shi Xiaoya,Lin Jie(The Affiliated Dongfeng Hospital of Hubei University of Medicine,Shiyan 442008,Hubei,China) |
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| Abstract: | Objective It is to evaluate the curative effect and safety of Reduning injection on infantile rotaviral enteritis.Methods Databases,including Chinese Hospital Digital Database and VIP,were searched,and randomized controlled trials of Reduning injection for infantile rotaviral enteritis were collected.Meta-analysis of the included trials was carried out to evaluate the efficacy of Reduning injection.Results A total of 1 528 patients involved in 11 papers was searched.The effective of Reduning injection group... |
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| Keywords: | Reduning injection rotaviral enteritis systematic evaluation Meta analysis |
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