养血妇康颗粒止血作用的实验研究

目的 :探讨养血妇康颗粒治疗产后出血的药理学作用基础。方法 :分别采用断尾出血法、毛细玻管法和复钙法观察养血妇康颗粒对动物出血时间和凝血时间的影响。结果 :养血妇康颗粒可显著缩短实验性类中医气血虚证小鼠断尾出血时间和凝血时间 ,以及正常大鼠断尾出血时间和家兔凝血时间。结论 :养血妇康颗粒治疗产后出血的机理中,除了可增强体质和提高产后子宫平滑肌收缩功能外 ,还具有提高机体凝血功能、增强止血的作用

Experimental Study on Hemostatic Action of Yang Xue Fu Kang Granules

OBJECTIVE:To explore the pharmacological basis of Yang Xue Fu Kang granules on the treatment of postpartum persistent hemorrhage METHODS:The methods such as bleeding with cutting tail,glass capillary and recalcification time were used to observe the effects of Yang Xue Fu Kang granules on the bleeding time and the clotting time of animals RESULTS:For the mice suffering from experimental deficiency of both qi and blood in Chinese medicine,Yang Xue Fu Kang granules obviously reduced both the bleeding time of tail wounds and the clotting time tested with glass capillary Also the drug reduced the bleeding time of tail wound in normal rats and clotting time(recalcification time)in normal rabbits CONCLUSION:Among the mechanisms of Yang Xue Fu Kang granules on treating postpartum persistent hemorrhage,promoting coagulation function and enhancing stypticity possess some positions