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Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1
Authors:Naotaka Tsutsumi  Qianhui Qu  Maša Mavri  Maibritt S. Baggesen  Shoji Maeda  Deepa Waghray  Christian Berg  Brian K. Kobilka  Mette M. Rosenkilde  Georgios Skiniotis  K. Christopher Garcia
Affiliation:1. Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA;2. Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA;3. Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA;4. Department of Biomedical Sciences, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark;5. Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia
Abstract:
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  • Keywords:G protein-coupled receptor  GPCR  Epstein-Barr virus  EBV  receptor  signaling  ligand-indpendent signaling  immune evasion  cryo-EM  G protein  viral GPCR
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