Digital tomosynthesis and ground glass nodules: Optimization of acquisition protocol. A phantom study |
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Authors: | E Baratella AM Bozzato C Marrocchio C Natali A Di Giusto E Quaia MA Cova |
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Institution: | 1. Department of Radiology, University of Trieste, Trieste, Italy;2. Department of Medicine, Surgery and Health Science, University of Trieste, Trieste, Italy;3. Department of Medicine - DIMED, Radiology Institute, University of Padua, Padua, Italy;4. Department of Radiology, Radiology of Gorizia and Monfalcone, Italy |
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Abstract: | IntroductionGround-glass nodules may be the expression of benign conditions, pre-invasive lesions or malignancies. The aim of our study was to evaluate the capability of chest digital tomosynthesis (DTS) in detecting pulmonary ground-glass opacities (GGOs).MethodsAn anthropomorphic chest phantom and synthetic nodules were used to simulate pulmonary ground-glass nodules. The nodules were positioned in 3 different regions (apex, hilum and basal); then the phantom was scanned by multi-detector CT (MDCT) and DTS. For each set (nodule-free phantom, nodule in apical zone, nodule in hilar zone, nodule in basal zone) seven different scans (n = 28) were performed varying the following technical parameters: Cu-filter (0.1–0.3 mm), dose rateo (10–25) and X-ray tube voltage (105–125 kVp). Two radiologists in consensus evaluated the DTS images and provided in agreement a visual score: 1 for unidentifiable nodules, 2 for poorly identifiable nodules, 3 for nodules identifiable with fair certainty, 4 for nodules identifiable with absolute certainty.ResultsIncreasing the dose rateo from 10 to 15, GGOs located in the apex and in the basal zone were better identified (from a score = 2 to a score = 3). GGOs located in the hilar zone were not visible even with a higher dose rate. Intermediate density GGOs had a good visibility score (score = 3) and it did not improve by varying technical parameters. A progressive increase of voltage (from 105 kVp to 125 kVp) did not provide a better nodule visibility.ConclusionDTS with optimized technical parameters can identify GGOs, in particular those with a diameter greater than 10 mm.Implications for practiceDTS could have a role in the follow-up of patients with known GGOs identified in lung apex or base region. |
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Keywords: | Digital tomosynthesis Ground-glass opacities Phantom Chest-X Ray (CXR)"} {"#name":"keyword" "$":{"id":"kwrd0030"} "$$":[{"#name":"text" "_":"Digital Tomosynthesis (DTS) Multi-detector CT (MDCT)"} {"#name":"keyword" "$":{"id":"kwrd0040"} "$$":[{"#name":"text" "_":"Thin-film transistors (TFT) Dose Area Product (DAP)"} {"#name":"keyword" "$":{"id":"kwrd0050"} "$$":[{"#name":"text" "_":"Detector Exposure Index (DEI) Dose Length Product (DLP)"} {"#name":"keyword" "$":{"id":"kwrd0060"} "$$":[{"#name":"text" "_":"X-ray tube voltage (kVp) X-ray tube current (mA)"} {"#name":"keyword" "$":{"id":"kwrd0070"} "$$":[{"#name":"text" "_":"X-ray tube current time (mAs) |
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