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Echocardiographic strain analysis reflects impaired ventricular function in youth with pediatric-onset systemic lupus erythematosus
Authors:Joyce C. Chang MD  MSCE  Yan Wang MD  Rui Xiao PhD  Anysia Fedec RDCS  Kevin E. Meyers MBBCh  Craig Tinker BS  Shobha S. Natarajan MD  Andrea M. Knight MD  MSCE  Pamela F. Weiss MD  MSCE  Laura Mercer-Rosa MD  MSCE
Affiliation:1. Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA;2. Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA;3. Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA;4. Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, USA;5. Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA;6. Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Division of Rheumatology, Hospital for Sick Children, Toronto, ON, Canada

SickKids Research Institute, Hospital for Sick Children, Toronto, ON, Canada

Department of Paediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada;7. Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA

Center for Pharmacoepidemiology Research and Training, University of Pennsylvania, Philadelphia, PA, USA

Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA

Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Abstract:
Keywords:echocardiography  left ventricular dysfunction  myocardial strain  pediatrics  speckle-tracking  systemic lupus erythematosus
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