| Affiliation: | 1. Department of Internal Medicine, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal;2. Department of Gastroenterology, Centro Hospitalar e Universitário Lisboa Norte, Lisboa, Portugal;3. Department of Gastroenterology, Centro Hospitalar de Vila Nova de Gaia e Espinho, Vila Nova de Gaia, Portugal;4. Department of Gastroenterology, Centro Hospitalar do Algarve, Hospital de Faro, Faro, Portugal;5. Department of Gastroenterology, Hospital Espírito Santo, Évora, Portugal;6. Biosystems and Integrative Science Institute (BioISI), Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisboa, Portugal;7. Laboratory of Biostatistics and Medical Informatics, Faculty of Medicine, University of Coimbra, Coimbra, Portugal;8. Instituto de Higiene e Medicina Social, Faculty of Medicine, University of Coimbra, Coimbra, Portugal;9. Centro de Estudos de Medicina Baseada na Evidência, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal |
