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The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men
Authors:Kimberly J. Nahon MD  Laura G. M. Janssen MD  Aashley S. D. Sardjoe Mishre MSc  Manu P. Bilsen MD  Jari A. van der Eijk BSc  Kani Botani MSc  Lisanne A. Overduin MD  Jonatan R. Ruiz PhD  Jedrzej Burakiewicz PhD  Oleh Dzyubachyk PhD  Andrew G. Webb PhD  Hermien E. Kan PhD  Jimmy F. P. Berbée PhD  Jan-Bert van Klinken PhD  Ko Willems van Dijk PhD  Michel van Weeghel PhD  Frédéric M. Vaz PhD  Tamer Coskun MD  Ingrid M. Jazet MD  Sander Kooijman PhD  Borja Martinez-Tellez PhD  Mariëtte R. Boon MD  Patrick C. N. Rensen PhD
Affiliation:1. Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands;2. Department of Radiology, C.J. Gorter Center for High Field MRI, Leiden, the Netherlands;3. Department of Physical Education and Sport, Faculty of Sport Sciences, PROFITH “PROmoting FITness and Health through physical activity” research group, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain;4. Department of Radiology, Division of Image Processing (LKEB), Leiden University Medical Center, Leiden, the Netherlands;5. Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands

Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology and Metabolism, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands

Core Facility Metabolomics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands;6. Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands;7. Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology and Metabolism, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands

Core Facility Metabolomics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands;8. Department of Diabetes/Endocrine, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, USA;9. Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands

Department of Physical Education and Sport, Faculty of Sport Sciences, PROFITH “PROmoting FITness and Health through physical activity” research group, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain;10. Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands

Abstract:
Keywords:brown adipose tissue  energy expenditure  lipid metabolism  metabolic disease  mirabegron  South Asian
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