CD_(56)在肿瘤病理诊断中的应用

CD56是神经细胞黏附分子中的一种,属免疫球蛋白超家族成员,是一组密切相关的唾液酸糖蛋白,在神经系统的生长发育中发挥重要作用。CD56与一些神经内分泌肿瘤关系密切,与多种肿瘤的进展和转移密切相关。目前较多应用在小细胞癌、肺癌、甲状腺肿瘤、前列腺癌、非霍奇金恶性淋巴瘤、造血性疾病的诊断与鉴别诊断及抗肿瘤的研究中。现就CD56在上述肿瘤病理诊断中的应用等方面作初步的阐述。

CD56 Application in Cancer Pathological Diagnosis

CD56 is a kind of nerve cell adhesion molecules,a member of immunoglobulin super family,a group of closely related saliva acid glycoproteins,which plays an important role in the growth and development of the nervous system.In recent years,it is found that CD56 is closely related with some neuroendocrine tumors tumor progression and metastasis,currently more used in the identification,diagnosis and anti-tumor research of small cell carcinoma,lung cancer,thyroid tumor,prostate cancer,non-hodgkin′s malignant lymphoma,and blood production disease.Here is to review on CD56 application in the pathological diagnosis of the above mentioned tumors.