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Phenytoin–induced toxic epidermal necrolysis: a case report
Authors:J.D. CREAMER  S.J. WHITTAKER  M. KERR-MUIR  N.P. SMITH
Affiliation:St John's Dermatology Centre, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH UK;Department of Ophthalmology, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH UK
Abstract:We present a case of phenytoin-induced toxic epidermal necrolysis resulting in 60–70% skin involvement. Systemic corticosteroids and prophylactic antibiotics used initially were discontinued, and subsequent management concentrated on intensive supportive treatment. The patient survived, but is left with disabling ocular complications.
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