黄芪、甘草治疗儿童感染后咳嗽的临床研究

目的 分析儿童感染后咳嗽的临床特点以及与外周血微量元素的关系.观察黄芪、甘草治疗儿童感染后咳嗽的疗效.方法 将75例患儿随机分为治疗组和对照组,治疗组39例,口服黄芪注射液和甘草合剂联合治疗;对照组36例,口服阿奇霉素治疗,观察两组临床疗效.对75例感染后咳嗽患儿与40例健康,bJL进行外周血微量元素测定,进行微量元素对比,结果75例患儿外周血铁、锌、镁均有不同程度的降低,治疗组疗效优于对照组,具有显著性差异(P＜0.05).治疗前后两组均未出现肝肾功损害.结论 感染后咳嗽发病可能与患儿血中微量元素铁、锌、镁降低有关,黄芪、甘草联合治疗儿童感染后咳嗽安全有效.

Clinical Study on Treatment of Infantile Post-infection Cough with Milkvetch Root and Radix Glycyrrhizae

Objective To analyze the relationship between clinical features of infantile cough after infection and microelements in peripheral blood, and to observe the therapeutic of treating this cough with Milkvetch Root and Radix Glycyrrhizae. Methods 75 infantile patients were randomly recruited into a therapeutic group and a reference group. 39 patients in the therapeutic group were treated with Huangqi Zhusheye and Tablete Glycyrrhiza, while 36 patients in the reference group were treated with Azithromycin. The therapeutic effects were evaluated after the treatment. Meanwhile,microelements in peripheral blood of the 75 patients were assayed and made a contrast to 40 healthy children. Results The contents of Fe, Zn, and Mg in peripheral blood of the 75 patients dropped on different levels, comparing to the healthy children.The therapeutic effects of the therapeutic group was much better than the reference group with significant difference (P＜0.05).Liver and renal functional lesion was unseen in both groups after the treatment. Conclusion Infantile past-infection cough may related with the decrease of Mg, Fe, and Zn. Combined usage of Milkvetch Root and Radix Glycyrrhizae clinically has good therapeutic effects to this disease.