| 冠心病不同程度冠脉狭窄时红细胞变形性和心功能变化及其意义 |
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| 引用本文： | 覃军,何作云,冯兵.冠心病不同程度冠脉狭窄时红细胞变形性和心功能变化及其意义[J].生物医学工程学杂志,1998,15(1):47-48,62. |
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| 作者姓名： | 覃军 何作云 冯兵 |
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| 作者单位： | 第三军区大学新桥医院临床血液流变学研究室!重庆400037 |
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| 摘 要： | 对冠心病（ＣＨＤ）按冠脉主要分支狭窄程度不同分组，测定红细胞变形指数（ＤＩ）和心功能参数（ＥＦ、ＦＳ）。结果表明，ＣＨＤ二亚组ＤＩ、ＥＦ、ＦＳ显著低于对照组（Ｐ＜００１或００５），ＣＨＤ冠脉明显狭窄组ＤＩ及ＥＦ、ＦＳ显著低于轻度狭窄组（Ｐ＜００５）。提示ＤＩ、ＥＦ、ＦＳ可能对于区别ＣＨＤ有或无意义冠脉狭窄具有一定预示价值。
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| 关 键 词： | 冠心病 冠脉狭窄 心功能 红细胞变形性 血液流变学 |
The Changes of Erythrocyte Deformability and Cardial Function in Coronary Heart Disease with Various Degrees of Coronary Stenosis |
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| Qin Jun,He Zuoyun,Feng Bin.The Changes of Erythrocyte Deformability and Cardial Function in Coronary Heart Disease with Various Degrees of Coronary Stenosis[J].Journal of Biomedical Engineering,1998,15(1):47-48,62. |
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| Authors: | Qin Jun He Zuoyun Feng Bin |
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| Institution: | Department of Clinical Hemorheology, Xingqiao Hospital, Third Military Med Univ, Chongqing 400037. |
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| Abstract: | According to the extent of coronary maximal stenosis, 29 cases of coronary heart disease (CHD) were classified into two groups: (I) obvious stenosis (OS, narrowing > or = 50% in luminal diameter, n = 15); (II) mild stenosis (MS, marrowing < 50% in luminal diameter, n = 14). The results showed that erythrocyte deformability index (DI), left ventricular ejection fraction (EF%) and fractional shortening (FS%) in the CHD patients were decreased as compared with those in the control group (P < 0.05 or 0.01), and the DI, EF and FS in the OS group were significantly lower than those in the MS group (P < 0.05). These suggest that DI, EF and FS may be of predictable value in identifying CHD patients with or without significant coronary stenosis. |
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| Keywords: | Cononary heart disease Erythrocyte deformability Left ventricular function |
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